EP 0281254 A1 19880907 - Antiarrythmic agents.
Title (en)
Antiarrythmic agents.
Title (de)
Antiarrhythmische Mittel.
Title (fr)
Agents antiarythmiques.
Publication
Application
Priority
- CA 567187 A 19880519
- GB 8702789 A 19870207
Abstract (en)
Compounds of the formula:- <CHEM> and their salts, where R is -NHSO2(C1-C4 alkyl), -NH2 or -NO2; R<1> is C1-C4 alkyl; and "Het" is a group of the formula:- <CHEM> where R<2> is H, CH3 or C2H5; R<3> is -NHSO2(C1-C4 alkyl), -NH2 or -NO2; and X is O, S or NR<4> where R<4> is H or CH3; with the proviso that when one of R and R<3> is -NO2, then the other is not -NH2. The compounds of the formula (A) in which both R and R<3> are -NHSO2(C1-C4 alkyl) are antiarrhythmic agents. The reamining compounds of the formula (A) are synthetic intermediates.
IPC 1-7
C07D 307/81; C07D 263/56; C07D 215/38; C07D 333/58; A61K 31/635
IPC 8 full level
A61K 31/34 (2006.01); A61K 31/343 (2006.01); A61K 31/38 (2006.01); A61K 31/381 (2006.01); A61K 31/40 (2006.01); A61K 31/403 (2006.01); A61K 31/404 (2006.01); A61K 31/42 (2006.01); A61K 31/423 (2006.01); A61K 31/425 (2006.01); A61K 31/428 (2006.01); A61K 31/47 (2006.01); A61P 9/06 (2006.01); C07D 209/14 (2006.01); C07D 215/12 (2006.01); C07D 215/38 (2006.01); C07D 235/06 (2006.01); C07D 263/56 (2006.01); C07D 277/64 (2006.01); C07D 307/81 (2006.01); C07D 333/58 (2006.01)
CPC (source: EP US)
A61P 9/06 (2017.12 - EP); C07D 215/38 (2013.01 - EP US); C07D 263/56 (2013.01 - EP US); C07D 307/81 (2013.01 - EP US); C07D 333/58 (2013.01 - EP US)
Citation (search report)
- [A] FR 2305179 A1 19761022 - LAFON LABOR [FR]
- [A] EP 0164697 A2 19851218 - KAKEN PHARMA CO LTD [JP]
- [AP] EP 0242173 A1 19871021 - PFIZER LTD [GB]
Designated contracting state (EPC)
AT BE CH DE ES FR GB GR IT LI LU NL SE
DOCDB simple family (publication)
EP 0281254 A1 19880907; EP 0281254 B1 19900117; AU 586139 B1 19890629; CA 1298840 C 19920414; DK 168382 B1 19940321; DK 58688 A 19880808; DK 58688 D0 19880205; ES 2013313 B3 19900501; IE 60349 B1 19940629; IE 880322 L 19880807; JP H0625122 B2 19940406; JP S63201167 A 19880819; US 4956382 A 19900911; US 5055473 A 19911008; US 5158964 A 19921027
DOCDB simple family (application)
EP 88300962 A 19880205; AU 1642588 A 19880519; CA 567187 A 19880519; DK 58688 A 19880205; ES 88300962 T 19880205; IE 32288 A 19880205; JP 2553788 A 19880205; US 15139088 A 19880202; US 52998490 A 19900529; US 72704091 A 19910708