EP 0288255 A2 19881026 - Method of producing phospholipid derivatives.
Title (en)
Method of producing phospholipid derivatives.
Title (de)
Verfahren zur Herstellung von Phospholipidderivate.
Title (fr)
Méthode de préparation de dérivés de phospholipides.
Publication
Application
Priority
JP 9624387 A 19870421
Abstract (en)
Phospholipid derivatives having two phosphatidyl residues in the molecule - which derivatives except for diphosphatidylglycerol are new compounds - are produced from a starting material phospholipid derivative by transphosphatidylation. In this method, a phospholipid derivative (I) represented by the formula <CHEM> is reacted with a chain polyhydric alcohol represented by the formula <CHEM> in the presence of a phospholipase D having a transphosphatidylation activity (EC 3.1.4.4), thereby extracting a phospholipid derivative represented by the following formula from the reaction mixture <CHEM> In the formulas, R1 and R2 represent acyl groups or alkyl groups, R3 represents an alkylene group (proviso, hydrogen atom may be substituted with a hydroxyl group, an alkoxyl group, a hydroxyalkyl group or the like), and X represents the organic residue remaining after the removal of one hydroxyl group of a compound containing hydroxyl group.
IPC 1-7
IPC 8 full level
A23J 7/00 (2006.01); C07F 9/10 (2006.01); C12P 7/6481 (2022.01); C12P 9/00 (2006.01)
CPC (source: EP US)
C07F 9/10 (2013.01 - EP); C12P 7/6481 (2013.01 - EP US); C12P 9/00 (2013.01 - EP)
Designated contracting state (EPC)
CH DE FR GB IT LI NL SE
DOCDB simple family (publication)
EP 0288255 A2 19881026; EP 0288255 A3 19900307; EP 0288255 B1 19940713; CA 1283075 C 19910416; DE 3850601 D1 19940818; DE 3850601 T2 19941201; JP 2657274 B2 19970924; JP S63263089 A 19881031
DOCDB simple family (application)
EP 88303542 A 19880420; CA 564062 A 19880413; DE 3850601 T 19880420; JP 9624387 A 19870421