Global Patent Index - EP 0302758 A1

EP 0302758 A1 19890208 - Viral expression inhibitors.

Title (en)

Viral expression inhibitors.

Title (de)

Virale Expressionsinhibitoren.

Title (fr)

Inhibiteurs d'expression viraux.

Publication

EP 0302758 A1 19890208 (EN)

Application

EP 88307302 A 19880808

Priority

US 8377187 A 19870807

Abstract (en)

A method of inhibiting the growth of a virus, the DNA of the virus including the nucleic acid sequence 5 min ACCXNNNPyCGGTXY3 min , where each N, X and Y is independently, any nucleotide, and Py is C or T, the nucleic acid sequence being capable of binding to a protein encoded by the DNA of the virus, the protein, upon binding to the nucleic acid sequence, being capable of causing the enhancement of the transcription of DNA of the virus, the method including inhibiting the protein from binding to the nucleic acid sequence to repress the transcription of DNA of said virus to inhibit the growth of the virus.

IPC 1-7

C12N 15/00; C12N 7/00

IPC 8 full level

C07H 21/04 (2006.01); C07K 14/01 (2006.01); C07K 14/025 (2006.01); C12N 7/04 (2006.01); C12N 15/09 (2006.01); C12N 15/11 (2006.01); C12N 15/113 (2010.01); C12N 15/37 (2006.01); A61K 38/00 (2006.01)

CPC (source: EP US)

A61K 31/70 (2013.01 - EP US); C07K 14/005 (2013.01 - EP US); C12N 15/1131 (2013.01 - EP US); A61K 38/00 (2013.01 - EP US); C07K 2319/00 (2013.01 - EP US); C12N 2310/13 (2013.01 - EP US); C12N 2710/20022 (2013.01 - EP US)

Citation (search report)

  • [AD] Cell, Vol. 42, No. 1, August 1985 (Cambridge, Mass., USA) B.A. SPALHOLZ et al. "Transactivation of a Bovine Papilloma Virus Transcriptional Regulatory Element by the E2 Gene Product" pages 183-191 * Totality *
  • [AD] Cell, Vol. 36, No. 2, February 1984 (Cambridge, Mass., USA) M. LUSKY et al. "Characterization of the bovine Papilloma Virus Plasmid Maintenance Sequences" pages 391-401 * Totality *

Designated contracting state (EPC)

AT BE CH DE ES FR GB GR IT LI LU NL SE

DOCDB simple family (publication)

EP 0302758 A1 19890208; EP 0302758 B1 19940316; AT E102993 T1 19940415; CA 1339596 C 19971223; DE 3888425 D1 19940421; DE 3888425 T2 19940623; ES 2061661 T3 19941216; JP H01137970 A 19890530; US 5674835 A 19971007

DOCDB simple family (application)

EP 88307302 A 19880808; AT 88307302 T 19880808; CA 573964 A 19880805; DE 3888425 T 19880808; ES 88307302 T 19880808; JP 19779888 A 19880808; US 47148495 A 19950606