EP 0302925 A4 19890424 - A METHOD FOR PRODUCING FACTOR VIII IN HIGH YIELD.
Title (en)
A METHOD FOR PRODUCING FACTOR VIII IN HIGH YIELD.
Title (de)
VERFAHREN ZUR HERSTELLUNG VOM FAKTOR VIII IN HOHER AUSBEUTE.
Title (fr)
PROCEDE DE PRODUCTION DU FACTEUR VIII EN GRANDE QUANTITE.
Publication
Application
Priority
US 923787 A 19870130
Abstract (en)
[origin: WO8805825A1] The method comprises the addition of vWf to the medium in which factor VIII-producing cells are grown. According to this method, increased amounts of both recombinant factor VIII and native factor VIII are purified from cells producing factor VIII.
IPC 1-7
IPC 8 full level
C12N 15/09 (2006.01); C07K 1/22 (2006.01); C07K 14/00 (2006.01); C07K 14/745 (2006.01); C07K 14/755 (2006.01); C12N 5/10 (2006.01); C12P 21/00 (2006.01); A61K 38/00 (2006.01); C12R 1/91 (2006.01)
CPC (source: EP KR)
C07K 14/755 (2013.01 - EP); C12P 21/00 (2013.01 - KR); A61K 38/00 (2013.01 - EP)
Citation (search report)
- [XP] EP 0251843 A1 19880107 - TRANSGENE SA [FR]
- [Y] THE JOURNAL OF CLINICAL INVESTIGATION, vol. 60, August 1977, pages 390-404; H.J. WEISS et al.: "Stabilization of factor VIII in plasma by the von Willebrand factor"
- [Y] BRITISH JOURNAL OF HAEMATOLOGY, vol. 52, 1982, pages 259-267, Blackwell Scientific Publications; E.G.D. TUDDENHAM et al.: "Response to infusions of polyelectrolyte fractionated human factor VIII concentrate in human haemophilia A and von Willebrand's disease"
- See references of WO 8805825A1
Designated contracting state (EPC)
AT BE CH DE FR GB IT LI LU NL SE
DOCDB simple family (publication)
WO 8805825 A1 19880811; AU 1340988 A 19880824; AU 606925 B2 19910221; EP 0302925 A1 19890215; EP 0302925 A4 19890424; JP 2872255 B2 19990317; JP H01501683 A 19890615; KR 890700671 A 19890426; NZ 223369 A 19900828
DOCDB simple family (application)
US 8800292 W 19880129; AU 1340988 A 19880129; EP 88902010 A 19880129; JP 50190888 A 19880129; KR 880701229 A 19880930; NZ 22336988 A 19880201