EP 0314720 A1 19890510 - PROCESS FOR SEPARATION OF FOLINIC ACIDS.
Title (en)
PROCESS FOR SEPARATION OF FOLINIC ACIDS.
Title (de)
VERFAHREN ZUR TRENNUNG VON FOLINSÄURE.
Title (fr)
PROCEDE DE SEPARATION D'ACIDES FOLINIQUES.
Publication
Application
Priority
CH 188387 A 19870515
Abstract (en)
[origin: WO8808844A1] A process makes possible the production of (6S) folinic acids and their salts by recrystallization of alkaline earth salts of (6R, S) folinic acids, possibly by release of these acids contained in alkaline earth folinates and/or possibly their conversion to alkali salts by at least one recrystallization in the presence of a base. The invention also concerns the (6S) folinates of calcium, magnesium, potassium and sodium and the (6S) folinic acids produced by the process described.
Abstract (fr)
Un procédé permet de produire des acides (6S) foliniques et leurs sels par recristallisation de sels alcalino-terreux des acides (6R, S) foliniques, éventuellement par libération de ces acides contenus dans des folinates alcalino-terreux et/ou éventuellement leur conversion en sels alcalins au moyen d'au moins une recristallisation en présence d'une base. L'invention concerne également des folinates (6S) de calcium, de magnésium, de potassium et de sodium et les acides (6S) foliniques produits selon le procédé décrit.
IPC 1-7
IPC 8 full level
C07D 475/04 (2006.01)
CPC (source: EP KR US)
C07D 475/04 (2013.01 - EP KR US)
Citation (search report)
See references of WO 8808844A1
Designated contracting state (EPC)
AT BE CH DE FR GB IT LI LU NL SE
DOCDB simple family (publication)
EP 0293029 A1 19881130; EP 0293029 B1 19910918; AR 243890 A1 19930930; AT E67498 T1 19911015; AU 1703188 A 19881206; AU 603673 B2 19901122; CA 1340290 C 19981229; CH 673459 A5 19900315; CN 1024553 C 19940518; CN 88102709 A 19881228; DD 270073 A5 19890719; DE 3864904 D1 19911024; DK 173708 B1 20010709; DK 254688 A 19881116; DK 254688 D0 19880509; EP 0314720 A1 19890510; ES 2040321 T3 19931016; FI 890195 A0 19890113; FI 890195 A 19890113; FI 93729 B 19950215; FI 93729 C 19950526; GR 3002756 T3 19930125; HU 201072 B 19900928; HU T49880 A 19891128; IE 60839 B1 19940824; IE 881450 L 19881115; JP H01503787 A 19891221; JP H089618 B2 19960131; KR 890700590 A 19890426; KR 950010074 B1 19950906; NZ 224361 A 19891027; PT 87355 A 19890630; PT 87355 B 19950301; US 5134235 A 19920728; US 5347005 A 19940913; US 6160116 A 20001212; WO 8808844 A1 19881117; ZA 883344 B 19881109
DOCDB simple family (application)
EP 88200864 A 19880422; AR 31083988 A 19880513; AT 88200864 T 19880422; AU 1703188 A 19880422; CA 566726 A 19880513; CH 188387 A 19870515; CN 88102709 A 19880511; DD 31567788 A 19880511; DE 3864904 T 19880422; DK 254688 A 19880509; EP 8800341 W 19880422; EP 88903810 A 19880422; ES 88200864 T 19880422; FI 890195 A 19890113; GR 910401367 T 19910919; HU 385188 A 19880422; IE 145088 A 19880513; JP 50380988 A 19880422; KR 880701643 A 19881210; NZ 22436188 A 19880422; PT 8735588 A 19880428; US 45969295 A 19950602; US 66868191 A 19910307; US 89648292 A 19920602; ZA 883344 A 19880511