EP 0320960 B1 19930512 - AMINO ANTHRACENEDIONES-BIS PLATINUM COMPLEXES, USEFUL AS ANTITUMORAL AGENTS
Title (en)
AMINO ANTHRACENEDIONES-BIS PLATINUM COMPLEXES, USEFUL AS ANTITUMORAL AGENTS
Publication
Application
Priority
- IT 2309487 A 19871218
- IT 4849288 A 19881026
Abstract (en)
[origin: EP0320960A1] Bis-platinum complexes of formula I <CHEM> wherein A is a disubstituted 1,4-anthracenedione; X, X min are ligands selected from the group consisting of Cl, Br, OH, CH3 SOCH3.OH or CH3SOCH3.Hal or, taken together, form the anion of a dicarboxylic acid; m is zero, 0.5 or an integer from 1 to 5; Solv is a solvent of crystallization; Ra is hydrogen, alkyl optionally substituted by hydroxy groups and/or interrupted by oxygen atoms; Rb is alkyl optionally substituted by hydroxy, alkoxy, polyalkoxy or sulphonic groups or a residue of an amino-sugar and n is an integer from 2 to 3. Compounds I are useful as anti-tumor agents.
IPC 1-7
IPC 8 full level
A61K 31/28 (2006.01); A61K 31/282 (2006.01); A61K 31/70 (2006.01); A61K 31/7135 (2006.01); A61P 35/00 (2006.01); C07F 15/00 (2006.01); C07H 23/00 (2006.01)
CPC (source: EP US)
A61P 35/00 (2017.12 - EP); C07F 15/0093 (2013.01 - EP US); C07H 23/00 (2013.01 - EP US)
Citation (examination)
EP 0169645 A1 19860129 - JOHNSON MATTHEY PLC [GB]
Designated contracting state (EPC)
AT BE CH DE ES FR GB GR IT LI LU NL SE
DOCDB simple family (publication)
EP 0320960 A1 19890621; EP 0320960 B1 19930512; AU 2817589 A 19890719; CA 1327355 C 19940301; DE 3880991 D1 19930617; DE 3880991 T2 19940105; EP 0396588 A1 19901114; ES 2056887 T3 19941016; JP H03503046 A 19910711; US 5145848 A 19920908; WO 8905815 A1 19890629
DOCDB simple family (application)
EP 88121072 A 19881216; AU 2817589 A 19891207; CA 586002 A 19881215; DE 3880991 T 19881216; EP 8801110 W 19881207; EP 89900592 A 19881207; ES 88121072 T 19881216; JP 50032588 A 19881207; US 49940590 A 19900614