Global Patent Index - EP 0321703 B1

EP 0321703 B1 19930428 - ABSORBENT FOR SERUM AMYLOID PROTEIN

Title (en)

ABSORBENT FOR SERUM AMYLOID PROTEIN

Publication

EP 0321703 B1 19930428 (EN)

Application

EP 88119263 A 19881119

Priority

  • JP 29481087 A 19871120
  • JP 29481187 A 19871120
  • JP 33061787 A 19871225

Abstract (en)

[origin: EP0321703A1] An adsorbent for a serum amyloid protein, which comprises a water-insoluble carrier and a compound selected from the group consisting of a compound having an anionic functional group, a polyanionic compound having more than one anionic functional groups, aniline and an aniline derivative, said compound being immobilized onto said carrier, or and a group of the formula: -NR<1>R<2>, wherein R<1> is hydrogen atom, methyl group or ethyl group, and R<2> is an atomic group satisfying that the value of log P, in which P is a distribution coefficient in a water-octanol system, of a compound of the formula: R<2>H is from 0 to 3.2, said group being bonded to said carrier, and a method for removing a serum amyloid protein from body fluid through a removing apparatus using the above adsorbent. According to the present invention, SA proteins, particularly SAA proteins and SAP proteins can be selectively removed from body fluid without decreasing HDL largely. Besides, the adsorbent can be provided at a low cost.

IPC 1-7

B01D 15/00; B01J 20/32

IPC 8 full level

B01D 15/00 (2006.01); B01J 20/32 (2006.01); A61M 1/34 (2006.01); A61M 1/36 (2006.01)

CPC (source: EP US)

A61M 1/3486 (2014.02 - EP US); B01D 15/00 (2013.01 - EP US); B01J 20/3204 (2013.01 - EP US); B01J 20/321 (2013.01 - EP US); B01J 20/3212 (2013.01 - EP US); B01J 20/3219 (2013.01 - EP US); B01J 20/3248 (2013.01 - EP US); B01J 20/3251 (2013.01 - EP US); B01J 20/3253 (2013.01 - EP US); B01J 20/3274 (2013.01 - EP US); B01J 20/328 (2013.01 - EP US); A61M 1/3679 (2013.01 - EP US)

Designated contracting state (EPC)

DE FR GB IT NL SE

DOCDB simple family (publication)

EP 0321703 A1 19890628; EP 0321703 B1 19930428; DE 3853219 D1 19950406; DE 3853219 T2 19950629; DE 3880647 D1 19930603; DE 3880647 T2 19931118; EP 0476721 A2 19920325; EP 0476721 A3 19920513; EP 0476721 B1 19950301; US 6037458 A 20000314

DOCDB simple family (application)

EP 88119263 A 19881119; DE 3853219 T 19881119; DE 3880647 T 19881119; EP 91119895 A 19881119; US 94847092 A 19920922