EP 0325460 A1 19890726 - Dideoxydidehydrocarbocyclic nucleosides.
Title (en)
Dideoxydidehydrocarbocyclic nucleosides.
Title (de)
Dideoxydidehydrocarbocyclische Nukleoside.
Title (fr)
Nucléosides didéoxydidéhydrocarbocycliques.
Publication
Application
Priority
- US 14625288 A 19880120
- US 27865288 A 19881205
Abstract (en)
Compounds of formula (I) <CHEM> (wherein X is hydrogen, NRR<1>, SR, OR or halogen; R and R<1> may be the same or different and are selected from hydrogen, C1-4alkyl and aryl) and pharmaceutically acceptable derivatives thereof are described having anticancer activity.
IPC 1-7
IPC 8 full level
A61K 31/505 (2006.01); A61K 31/52 (2006.01); A61K 31/522 (2006.01); A61P 35/00 (2006.01); C07D 473/16 (2006.01); C07D 473/18 (2006.01); C07D 473/24 (2006.01); C07D 473/32 (2006.01); C07D 473/40 (2006.01); C07D 487/04 (2006.01)
CPC (source: EP US)
A61P 35/00 (2017.12 - EP); C07D 487/04 (2013.01 - EP US)
Citation (applicant)
- US 4383114 A 19830510 - VINCE ROBERT
- US 4138562 A 19790206 - VINCE ROBERT
- "Protective Groups in Organic Chemistry", 1973, PLENUM PRESS
- THEODORA W. GREENE: "Protective Groups in Organic Synthesis", 1981, JOHN WILEY AND SONS
- HARRISON: "Compendium of Organic Synthetic Methods", 1971, WILEY-INTERSCIENCE, pages: 250 - 252
- G. G. URQUART, ORG. SYN. COLL., vol. 3, 1953, pages 363
- J. R. MARSHALL, J.. CHEM. SOC., 1951, pages 1004
- V. NAIR, J. ORG. CHEM., vol. 52, 1987, pages 1344
- "Nucleoside Analogs - Chemistry, Biology and Medichl Applications", 1979, PLENUM PLESS, pages: 193 - 223
- E. L. ELIEL: "Stereochemistry of Carbon Compounds", 1962, MCGRAW HILL
- S. H. WILEN., TABLES OF RESOLVING AGENTS
- R. G. ALMQUIST; R. VINCE, J. MED. CHEM., vol. 16, 1973, pages 1396
Citation (search report)
- [A] EP 0215759 A1 19870325 - UNIV MINNESOTA [US]
- [A] US 4268672 A 19810519 - VINCE ROBERT
- [A] EP 0236935 A2 19870916 - TAKEDA CHEMICAL INDUSTRIES LTD [JP]
- [AD] JOURNAL OF ORGANIC CHEMISTRY
Designated contracting state (EPC)
AT BE CH DE ES FR GB GR IT LI LU NL SE
DOCDB simple family (publication)
EP 0325460 A1 19890726; EP 0325460 B1 19921021; AT E81653 T1 19921115; CA 1339803 C 19980407; DE 68903226 D1 19921126; DE 68903226 T2 19930304; ES 2052897 T3 19940716; GR 3006490 T3 19930621; JP 2738946 B2 19980408; JP H01308282 A 19891212; PH 30732 A 19971017; US 4931559 A 19900605
DOCDB simple family (application)
EP 89300510 A 19890119; AT 89300510 T 19890119; CA 588611 A 19890119; DE 68903226 T 19890119; ES 89300510 T 19890119; GR 920402846 T 19921209; JP 874589 A 19890119; PH 38069 A 19890119; US 27865288 A 19881205