EP 0328524 B1 19931118 - TRANSDERMAL FERTILITY CONTROL SYSTEM AND PROCESS.
Title (en)
TRANSDERMAL FERTILITY CONTROL SYSTEM AND PROCESS.
Title (de)
SYSTEM UND VERFAHREN ZUR TRANSKUTANEN FRUCHTBARKEITSKONTROLLE.
Title (fr)
PROCEDE ET SYSTEME DE REGULATION TRANDSERMIQUE DE LA FERTILITE.
Publication
Application
Priority
US 90244086 A 19860829
Abstract (en)
[origin: WO8801496A1] Transdermal fertility-controlling absorption polymer matrix dosage units have been developed which comprise a backing layer, an adjoining layer of a solid polymer matrix in which minimum effective daily doses of an estrogen and a progestin are microdispersed and released for transdermal absorption. Presently preferred is use of the natural estrogen, 17-beta-estradiol, and of the progestin, levonorgestrel. The units have a biologically acceptable adhesive polymer layer. The polymer matrix as well as the adhesive layer can have dispersed one or more skin permeation enhancers. Dosage units are provided which transdermally deliver at least minimum daily doses of the estrogen and progestin for multiple days, such as for one week. The invention also provides a process of fertility control using the novel polymer matrix dosage units for the first three weeks of consecutive menstrual cycles of the subject desiring fertility control.
IPC 1-7
IPC 8 full level
A61K 9/70 (2006.01); A61K 31/565 (2006.01); A61K 31/57 (2006.01)
CPC (source: EP KR US)
A61F 13/00 (2013.01 - KR); A61K 9/7069 (2013.01 - EP US); A61K 9/7084 (2013.01 - EP US)
Designated contracting state (EPC)
AT BE CH DE FR GB IT LI LU NL SE
DOCDB simple family (publication)
WO 8801496 A1 19880310; AU 1738092 A 19920730; AU 621034 B2 19920305; AU 659457 B2 19950518; AU 7916287 A 19880324; CA 1310268 C 19921117; DE 3788226 D1 19931223; DE 3788226 T2 19940505; DK 231588 A 19880614; DK 231588 D0 19880428; EP 0328524 A1 19890823; EP 0328524 A4 19900222; EP 0328524 B1 19931118; FI 890945 A0 19890228; FI 890945 A 19890228; JP 2573638 B2 19970122; JP H02500740 A 19900315; KR 880701535 A 19881103; KR 950008164 B1 19950726; US 4818540 A 19890404
DOCDB simple family (application)
US 8702142 W 19870828; AU 1738092 A 19920602; AU 7916287 A 19870828; CA 545628 A 19870828; DE 3788226 T 19870828; DK 231588 A 19880428; EP 87905994 A 19870828; FI 890945 A 19890228; JP 50548387 A 19870828; KR 880700464 A 19880429; US 90244086 A 19860829