Global Patent Index - EP 0334966 B1

EP 0334966 B1 19940824 - PROCESS FOR SYNTHESIZING OPTICALLY ACTIVE COMPOUNDS.

Title (en)

PROCESS FOR SYNTHESIZING OPTICALLY ACTIVE COMPOUNDS.

Title (de)

VERFAHREN ZUR HERSTELLUNG OPTISCH AKTIVER VERBINDUNGEN.

Title (fr)

PROCEDE DE SYNTHESE DE COMPOSES OPTIQUEMENT ACTIFS.

Publication

EP 0334966 B1 19940824

Application

EP 88908336 A 19880916

Priority

  • JP 8800945 W 19880916
  • JP 23077388 A 19880914
  • JP 23530087 A 19870918

Abstract (en)

[origin: WO8902470A1] A process for synthesizing optically active compounds by asymmetric hydrolysis of a carbinol derivative having a fluorine atom or a fluoroalkyl group using an enzyme as a catalyst, which comprises immobilizing the enzyme on a honeycomb structure of porous ceramics, bringing said carbinol derivative into contact with the immobilized enzyme to conduct asymmetric hydrolysis and, after the reaction has proceeded to a predetermined extent, discontinuing the contact between the enzyme and the carbinol derivatives.

IPC 1-7

C12P 7/62; C12P 41/00

IPC 8 full level

C12N 11/14 (2006.01); C12P 7/02 (2006.01); C12P 41/00 (2006.01)

CPC (source: EP)

C12N 11/14 (2013.01); C12P 7/02 (2013.01); C12P 41/004 (2013.01)

Citation (examination)

  • CHEMICAL ABSTRACTS, vol. 102, no. 9, 04 March 1985, Columbus, OH (US); T. KITAZUME et al., no. 75208g#
  • CHEMICAL ABSTRACTS, vol. 107, no. 11, 14 September 1987, Columbus, OH (US); LIN Jenq Tain et al., no. 95238y#

Designated contracting state (EPC)

DE FR GB

DOCDB simple family (publication)

WO 8902470 A1 19890323; DE 3851218 D1 19940929; DE 3851218 T2 19950223; EP 0334966 A1 19891004; EP 0334966 A4 19911002; EP 0334966 B1 19940824; JP H01157398 A 19890620; JP H0716437 B2 19950301

DOCDB simple family (application)

JP 8800945 W 19880916; DE 3851218 T 19880916; EP 88908336 A 19880916; JP 23077388 A 19880914