Global Patent Index - EP 0344257 A4

EP 0344257 A4 19900409 - RHOPTRY ANTIGEN OF -i(PLASMODIUM FALCIPARUM).

Title (en)

RHOPTRY ANTIGEN OF -i(PLASMODIUM FALCIPARUM).

Title (de)

RHOPTRY ANTIGEN VON -i(PLASMODIUM FALCIPARUM).

Title (fr)

ANTIGENE TOXONEMIQUE DE -i(PLASMODIUM FALCIPARUM).

Publication

EP 0344257 A4 19900409 (EN)

Application

EP 89900001 A 19881201

Priority

AU PI568687 A 19871201

Abstract (en)

[origin: WO8905348A1] A rhoptry antigen of the asexual blood stages of $i(Plasmodium falciparum), is characterised by: (i) having an apparent molecular weight of approximately 55kDa; (ii) being a glycoprotein incorporating myristic acid; (iii) being present in a restricted localisation with merozoites consistent with a rhoptry location; and (iv) being extracted into the detergent phase when parasite antigens are separated by phase partitioning with detergent.

IPC 1-7

A61K 37/02; C07H 21/04; C07K 13/00; C07K 15/12; C07K 15/14; C12N 15/00; C12P 21/02

IPC 8 full level

C12N 15/09 (2006.01); A61K 39/015 (2006.01); C07K 14/005 (2006.01); C07K 14/195 (2006.01); C07K 14/44 (2006.01); C07K 14/445 (2006.01); C12N 1/21 (2006.01); C12N 15/30 (2006.01); C12P 21/00 (2006.01); C12P 21/02 (2006.01); A61K 39/00 (2006.01); C12R 1/19 (2006.01); C12R 1/90 (2006.01)

CPC (source: EP KR US)

A61K 39/015 (2013.01 - EP); C07K 14/445 (2013.01 - EP); C12N 15/00 (2013.01 - KR); A61K 39/00 (2013.01 - EP KR US); Y02A 50/30 (2018.01 - EP)

Citation (search report)

  • [X] WO 8402917 A1 19840802 - INST MEDICAL W & E HALL [AU]
  • [A] WO 8503725 A1 19850829 - BIOGEN NV [NL]
  • [XP] PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCE, vol. 85, July 1988, pages 5195-5199, Washington, D.C., US; J.A. SMYTHE et al.: "Identification of two integral membrane proteins of Plasmodium falciparum"
  • [A] BIOTECHNOLOGY, vol. 3, no. 8, August 1985, pages 729-740, New York US; J.V. RAVETCH et al.:"Molecular genetic strategies for the development of anti-malarial vaccines"
  • [A] MOLECULAR AND BIOCHEMICAL PARASITOLOGY, vol. 25, 1987, pages 73-81, Elsevier Science Publishers, Amsterdam, NL; R.L. COPPEL et al.: "A cDNA clone expressing a rhoptry protein of Plasmodium falciparum"
  • See also references of WO 8905348A1

Designated contracting state (EPC)

AT BE CH DE FR GB IT LI LU NL SE

DOCDB simple family (publication)

WO 8905348 A1 19890615; AU 2609588 A 19890705; AU 608096 B2 19910321; EP 0344257 A1 19891206; EP 0344257 A4 19900409; GB 2220943 A 19900124; GB 8916546 D0 19891101; IL 88558 A0 19890731; JP H02502337 A 19900802; KR 900700599 A 19900816; ZA 888983 B 19890830

DOCDB simple family (application)

AU 8800463 W 19881201; AU 2609588 A 19881201; EP 89900001 A 19881201; GB 8916546 A 19881201; IL 8855888 A 19881201; JP 50001089 A 19881201; KR 890701431 A 19890731; ZA 888983 A 19881130