EP 0346445 A4 19900328 - DEXTRORPHAN POTENTIATOR FOR ANTICONVULSANT COMPOSITION AND METHOD.
Title (en)
DEXTRORPHAN POTENTIATOR FOR ANTICONVULSANT COMPOSITION AND METHOD.
Title (de)
DEXTROPHAN-BEKRÄFTIGER FÜR ANTISPASMENZUBEREITUNGEN UND VERFAHREN.
Title (fr)
POTENTIALISATEUR DE DEXTRORPHANE POUR COMPOSITIONS ANTISPASMODIQUES ET PROCEDES.
Publication
Application
Priority
US 13656487 A 19871222
Abstract (en)
[origin: WO8905642A1] A pharmaceutical composition including an active anticonvulsant drug and an effective amount of at least one metabolite of dextromethorphan sufficient to potentiate the anticonvulsant activity of the anticonvulsant drug. The metabolites and in particular dextrorphan are effective in potentiating the activity of anticonvulsants including phenytoin and carbamazepine. A method of treating epilepsy and other forms of convulsions comprising administration either simultaneously or sequentially and of an effective amount of an anticonvulsant drug and at least one of the dextromethorphan metabolites in an amount sufficient to potentiate the action of the anticonvulsant drug.
IPC 1-7
IPC 8 full level
A61K 31/415 (2006.01); A61K 31/42 (2006.01); A61K 31/445 (2006.01); A61K 31/485 (2006.01); A61K 31/495 (2006.01); A61K 31/535 (2006.01); A61K 31/55 (2006.01); A61K 31/655 (2006.01); A61K 45/00 (2006.01); A61P 25/00 (2006.01); A61P 25/08 (2006.01)
CPC (source: EP)
A61K 31/415 (2013.01); A61K 31/42 (2013.01); A61K 31/485 (2013.01); A61K 31/535 (2013.01); A61K 31/55 (2013.01); A61K 31/655 (2013.01); A61P 25/00 (2017.12); A61P 25/08 (2017.12)
Citation (search report)
- No relevant documents have been disclosed.
- See references of WO 8905642A1
Designated contracting state (EPC)
AT BE CH DE FR GB IT LI LU NL SE
DOCDB simple family (publication)
WO 8905642 A1 19890629; AU 2929489 A 19890719; EP 0346445 A1 19891220; EP 0346445 A4 19900328; JP H02502546 A 19900816
DOCDB simple family (application)
US 8804539 W 19881219; AU 2929489 A 19891219; EP 89901396 A 19881219; JP 50135389 A 19881219