Global Patent Index - EP 0349594 A4

EP 0349594 A4 19900926 - RECOMBINANT BACULOVIRUS OCCLUSION BODIES IN VACCINES AND BIOLOGICAL INSECTICIDES

Title (en)

RECOMBINANT BACULOVIRUS OCCLUSION BODIES IN VACCINES AND BIOLOGICAL INSECTICIDES

Publication

EP 0349594 A4 19900926 (EN)

Application

EP 88904294 A 19880302

Priority

  • US 2649887 A 19870316
  • US 2649987 A 19870316
  • US 15373688 A 19880208

Abstract (en)

[origin: WO8807082A1] The present invention is directed to recombinant baculoviruses which encode fusion polyhedrin proteins capable of forming occlusion bodies containing foreign peptides. The recombinant baculoviruses of the invention are formed by insertion into or replacement of regions of the polyhedrin gene that are not essential for occlusion body formation, with foreign DNA fragments by recombinant DNA techniques. The recombinant occlusion bodies produced in accordance with the present invention have uses in vaccine formulations, immunoassays, immobilized enzyme reactions, as biological insecticides, and as expression vectors.

IPC 1-7

C12N 15/00; A61K 39/12

IPC 8 full level

C12N 15/09 (2006.01); C07K 14/00 (2006.01); C07K 14/01 (2006.01); C07K 14/02 (2006.01); C07K 14/10 (2006.01); C07K 14/11 (2006.01); C07K 14/18 (2006.01); C07K 19/00 (2006.01); C12N 7/00 (2006.01); C12N 15/866 (2006.01); C12P 21/02 (2006.01); A61K 39/00 (2006.01); C12R 1/91 (2006.01)

CPC (source: EP)

C07K 14/005 (2013.01); C12N 15/86 (2013.01); A61K 39/00 (2013.01); C07K 2319/00 (2013.01); C07K 2319/09 (2013.01); C07K 2319/10 (2013.01); C07K 2319/55 (2013.01); C07K 2319/61 (2013.01); C07K 2319/735 (2013.01); C12N 2710/14143 (2013.01); C12N 2760/16122 (2013.01); C12N 2760/16134 (2013.01); Y02A 50/30 (2018.01)

Citation (search report)

  • [X] EP 0127839 A2 19841212 - TEXAS A & M UNIV SYS [US]
  • [YP] PROTEIN ENGINEERING, vol. 1, no. 4, August/September 1987, pages 359-366, IRL Press Ltd, Oxford, GB; V.C. EMERY et al.: "The development of multiple expression vectors for high level synthesis of eukaryotic proteins: expression of LCMV-N and AcNPV polyhedrin protein by a recombinant baculovirus"
  • [Y] EMBO JOURNAL, vol. 5, no. 6, 1986, pages 1359-1365, IRL Press Ltd, Oxford, GB; K. KURODA et al.: "Expression of the influenza virus haemagglutinin in insect cells by a baculovirus vector"
  • See also references of WO 8807082A1

Designated contracting state (EPC)

AT BE CH DE FR GB IT LI LU NL SE

DOCDB simple family (publication)

WO 8807082 A1 19880922; AU 1717688 A 19881010; EP 0349594 A1 19900110; EP 0349594 A4 19900926; JP H02502876 A 19900913

DOCDB simple family (application)

US 8800631 W 19880302; AU 1717688 A 19880302; EP 88904294 A 19880302; JP 50402888 A 19880302