EP 0353614 A2 19900207 - Confirmatory assay for Chlamydia trachomatis.
Title (en)
Confirmatory assay for Chlamydia trachomatis.
Title (de)
Bestätigender Nachweis für Chlamydia trachomatis.
Title (fr)
Essai confirmatif pour Chlamydia trachomatis.
Publication
Application
Priority
US 22836388 A 19880804
Abstract (en)
In an assay where a ligand or organism is detected by a detector binding protein ("DBP") capable of generating a signal in proportion to the amount of ligand or organism bound to the DBP, the presence of the ligand or organism is confirmed by the use, prior to or concurrently with the DBP, of a confirmatory binding protein ("CBP") which binds to a second site on the ligand or organism, and thereby prevents the DBP from binding to the first site. Thus, a reduction in signal of a predetermined amount indicates the true presence of the ligand or organism, while failure to obtain signal reduction of a predetermined amount indicates that the original signal was a false positive due to assay artifact or detection of related ligands or organisms. In a preferred embodiment, the CBP is a monoclonal antibody and the organism is derived from Chlamydia species.
IPC 1-7
IPC 8 full level
G01N 33/536 (2006.01); G01N 33/542 (2006.01); G01N 33/543 (2006.01); G01N 33/569 (2006.01)
CPC (source: EP KR US)
G01N 33/53 (2013.01 - KR); G01N 33/542 (2013.01 - EP US); G01N 33/56927 (2013.01 - EP US)
Designated contracting state (EPC)
AT BE CH DE ES FR GB IT LI NL
DOCDB simple family (publication)
EP 0353614 A2 19900207; EP 0353614 A3 19901114; EP 0353614 B1 19941109; AT E114049 T1 19941115; AU 3927989 A 19900208; AU 620126 B2 19920213; CA 1339769 C 19980324; DE 68919294 D1 19941215; DE 68919294 T2 19950614; JP 2812995 B2 19981022; JP H02112764 A 19900425; KR 900003630 A 19900326; US 5064755 A 19911112
DOCDB simple family (application)
EP 89113783 A 19890726; AT 89113783 T 19890726; AU 3927989 A 19890803; CA 607326 A 19890802; DE 68919294 T 19890726; JP 20370089 A 19890803; KR 890011074 A 19890803; US 22836388 A 19880804