EP 0367944 A2 19900516 - Ether derivative of 4-¬3H -quinazolinone, a process for the preparation thereof, and pharmaceutical compositions
Title (en)
Ether derivative of 4-¬3H -quinazolinone, a process for the preparation thereof, and pharmaceutical compositions
Title (de)
Ätherderivate von 4-¬3H -Chinazolinon, Verfahren zu deren Herstellung und pharmazeutische Zusammenstellungen
Title (fr)
Dérivés éthérés de 4-¬3H -quinazolinone, procédé pour leur préparation et compositions pharmaceutiques
Publication
Application
Priority
CS 719588 A 19881101
Abstract (en)
The invention relates to 3-[2-(2 min ,4 min -difluoro-4-biphenylyloxy)-ethyl]-4-[3H]-quinazolinone and its acid addition salts, particularly the hydrochloride, to a process for preparing these compounds and intermediates thereof, and to pharmaceutical compositions comprising these compounds as active ingredients. The ether derivative of 4-[3H]-quinazolinone according to the invention possesses considerably higher analgesic activity and lower acute toxicity than aminophenazone, ibuprofen, acetylosalicylic acid and paracetamol.
IPC 1-7
IPC 8 full level
C07D 239/88 (2006.01); A61K 31/505 (2006.01); A61K 31/517 (2006.01); A61P 25/04 (2006.01); C07C 39/367 (2006.01); C07C 43/225 (2006.01); C07D 239/90 (2006.01)
CPC (source: EP US)
A61P 25/04 (2017.12 - EP); C07C 39/367 (2013.01 - EP US); C07C 43/225 (2013.01 - EP US); C07D 239/90 (2013.01 - EP US)
Designated contracting state (EPC)
AT BE CH DE FR GB IT LI LU NL SE
DOCDB simple family (publication)
EP 0367944 A2 19900516; EP 0367944 A3 19901205; AU 4288089 A 19900510; CA 1316924 C 19930427; CS 272018 B1 19901213; CS 719588 A1 19900314; JP H02172977 A 19900704; US 4973691 A 19901127
DOCDB simple family (application)
EP 89116865 A 19890912; AU 4288089 A 19891013; CA 609601 A 19890828; CS 719588 A 19881101; JP 28314789 A 19891101; US 43029389 A 19891101