EP 0378615 A1 19900725 - NUCLEOSIDE AND POLYNUCLEOTIDE THIOPHOSPHORAMIDITE AND PHOSPHORODITHIOATE COMPOUNDS AND PROCESSES.
Title (en)
NUCLEOSIDE AND POLYNUCLEOTIDE THIOPHOSPHORAMIDITE AND PHOSPHORODITHIOATE COMPOUNDS AND PROCESSES.
Title (de)
NUKLEOSID- UND POLYNUKLEOTID THIOPHOSPHORAMIDIT- UND PHOSPHORODITHIOATVERBINDUNGEN UND VERFAHREN.
Title (fr)
COMPOSES DE THIOPHOSPHORAMIDITE ET DE PHOSPHORODITHIOATE DE NUCLEOSIDES ET DE POLYNUCLEOTIDES ET PROCEDES.
Publication
Application
Priority
- US 19888688 A 19880526
- US 31401189 A 19890222
Abstract (en)
[origin: WO8911486A1] The present invention relates to new and useful nucleoside thiophosphoramidite, polynucleotide dithioate phosphoramidite and polynucleotide phosphorthioamidate phosphoramidite compounds as well as the processes whereby these compounds can be used for synthesizing new mononucleotides and polynucleotides having phosphorodithioate, phosphorothioamidate, phosphorothiotriesters, and phosphorothioate internucleotide linkages.
Abstract (fr)
Cette invention concerne des composés nouveaux et utiles de thiophosphoramidite de nucléosides, de phosphoramidite de dithioate de polynucléotides et de phosphoramidite de phosphorthioamidate de polynucléotides, ainsi que les procédés selon lesquels on peut utiliser ces composés pour synthétiser de nouveaux mononucléotides et polynucléotides ayant du phosphorodithioate, du phosphorothioamidate, des phosphorothiotriesters, et des liaisons internucléotides de phosphorothioate.
IPC 1-7
IPC 8 full level
C07H 1/02 (2006.01); C07H 19/04 (2006.01); C07H 19/10 (2006.01); C07H 19/20 (2006.01); C07H 21/00 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01)
CPC (source: EP KR)
C07H 17/00 (2013.01 - KR); C07H 19/10 (2013.01 - EP); C07H 19/20 (2013.01 - EP); C07H 21/00 (2013.01 - EP); C07H 21/02 (2013.01 - EP); C07H 21/04 (2013.01 - EP)
Designated contracting state (EPC)
AT BE CH DE FR GB IT LI LU NL SE
DOCDB simple family (publication)
WO 8911486 A1 19891130; AU 3739289 A 19891212; AU 626305 B2 19920730; EP 0378615 A1 19900725; EP 0378615 A4 19920408; ES 2015665 A6 19900901; IL 90359 A0 19891215; JP H03501128 A 19910314; KR 900701813 A 19901204
DOCDB simple family (application)
US 8902293 W 19890525; AU 3739289 A 19890525; EP 89906571 A 19890525; ES 8901786 A 19890526; IL 9035989 A 19890519; JP 50639789 A 19890525; KR 900700156 A 19900129