Title (en)

INTERLEUKIN II ANALOGS

Publication

EP 0378666 A4 19920122 (EN)

Application

EP 89908361 A 19890705

Priority

US 21499888 A 19880705

Abstract (en)

[origin: WO9000565A1] Interleukin II analogs and DNA sequences comprising structural genes coding for such analogs which differ from the naturally-occurring forms in terms of the identity and/or location of one or more amino acids are disclosed.

IPC 1-7

C07K 13/00; C07K 17/00; C07K 3/26; A61K 45/00; C12N 15/00; C07H 17/00; C07H 21/04

IPC 8 full level

A61K 38/00 (2006.01); A61K 39/395 (2006.01); A61P 37/00 (2006.01); C07H 21/04 (2006.01); C07K 14/52 (2006.01); C07K 14/54 (2006.01); C07K 14/55 (2006.01); C07K 16/00 (2006.01); C07K 19/00 (2006.01); C12N 1/21 (2006.01); C12N 15/09 (2006.01); C12N 15/26 (2006.01); C12P 21/02 (2006.01); C12P 21/08 (2006.01); C12R 1/19 (2006.01)

CPC (source: EP)

A61P 37/00 (2017.12); C07K 14/55 (2013.01); A61K 38/00 (2013.01)

Citation (search report)

• [X] BIOLOGY CHEMISTRY HOPPE-SEYLER, vol. 368, no. 9, 1987, page 1060; R. H\FER et al.: "Modification and introduction of protein glycosylation sites by site-specific mutagenesis: Studies on human interleukin 2"
• [A] JOURNAL OF CELLULAR BIOCHEMISTRY-UCLA SYMPOSIA ON MOLECULAR & CELLULAR BIOLOGY, 15th ANNUAL MEETINGS, Suppl. 10A, 20th January-15th February 1986, page 77, abstract no. B32, Alan R. Liss, Inc., New York, US; G. JU et al.: "Site-directed mutagenesis of the human interleukin-2 gene product: Identification of amino acid residues required for biological activity"
• See references of WO 9000565A1

Designated contracting state (EPC)

AT BE CH DE FR GB IT LI LU NL SE

DOCDB simple family (publication)

WO 9000565 A1 19900125; AU 3877689 A 19900205; AU 627477 B2 19920827; EP 0378666 A1 19900725; EP 0378666 A4 19920122; JP H03500415 A 19910131

DOCDB simple family (application)

US 8902917 W 19890705; AU 3877689 A 19890705; EP 89908361 A 19890705; JP 50803889 A 19890705