Global Patent Index - EP 0384731 B1

EP 0384731 B1 19961218 - Osteogenic growth polypeptides identified from regenerating bone marrow

Title (en)

Osteogenic growth polypeptides identified from regenerating bone marrow

Title (de)

Osteogenische Wachstumfaktoren, die aus sich regenerierendem Knochenmark identifiziert werden

Title (fr)

Facteurs de croissance ostéogéniques identifiés à partir de moelle osseuse régénératrice

Publication

EP 0384731 B1 19961218 (EN)

Application

EP 90301862 A 19900221

Priority

US 31460289 A 19890223

Abstract (en)

[origin: EP0384731A2] The present invention comprises a biochemically pure polypeptide(s), termed osteogenic growth polypeptide (OGP), which exhibits stimulatory effects on osteoblastlc cells and in vivo bone formation. OGP, identified from regenerating bone marrow, has an amino acid sequence of Ala-Leu-Lys-Arg-Gln-Gly-Arg-Thr-Leu-Tyr-Gly-Phe-Gly-Gly s

IPC 1-7

C07K 7/00; C07K 4/12; A61K 38/04; A61K 38/03; C07K 1/14; G01N 33/50

IPC 8 full level

G01N 33/68 (2006.01); A61K 38/00 (2006.01); A61P 19/10 (2006.01); A61P 43/00 (2006.01); C07K 1/14 (2006.01); C07K 1/20 (2006.01); C07K 1/22 (2006.01); C07K 7/06 (2006.01); C07K 7/08 (2006.01); C07K 14/435 (2006.01); C07K 14/51 (2006.01)

CPC (source: EP)

A61P 19/10 (2017.12); A61P 43/00 (2017.12); C07K 14/51 (2013.01); A61K 38/00 (2013.01)

Citation (examination)

  • CHEMICAL ABSTRACTS, vol. 74, no. 1, 4 January 1971, Columbus, Ohio, USA, page 169; Sautiere et al
  • CHEMICAL ABSTRACTS, vol. 76, no. 7, 14 February 1972, Columbus, Ohio, USA; Sautiere P. et al: "Primary structure of the glycine- and arginine- rich histone isolated from rat chloroleukemic tumor", page 98

Designated contracting state (EPC)

CH DE FR GB IT LI NL

DOCDB simple family (publication)

EP 0384731 A2 19900829; EP 0384731 A3 19910626; EP 0384731 B1 19961218; CA 2010660 A1 19900823; CA 2010660 C 19900823; DE 69029415 D1 19970130; DE 69029415 T2 19970403; JP H02282396 A 19901119; JP H07103156 B2 19951108

DOCDB simple family (application)

EP 90301862 A 19900221; CA 2010660 A 19900222; DE 69029415 T 19900221; JP 4428790 A 19900223