Global Patent Index - EP 0391796 A1

EP 0391796 A1 19901010 - New imidazole derivatives, process for their production and pharmaceutical compositions containing them.

Title (en)

New imidazole derivatives, process for their production and pharmaceutical compositions containing them.

Title (de)

Imidazol-Derivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzung.

Title (fr)

Dérivés de l'imidazole, procédé pour leur préparation et compositions pharmaceutiques les contenant.

Publication

EP 0391796 A1 19901010 (FR)

Application

EP 90400918 A 19900404

Priority

GB 8907656 A 19890405

Abstract (en)

The invention provides: (2S,4R,6S)-6-Ä(4,5-diphenylimidazol-2-yl)thiomethylÜ-4-hydroxy-2-metho xy-3,4,5,6-tetrahydro-2H-pyran and (2R,4R,6S)-6-Ä(4,5-diphenylimidazol-2-yl)thiomethylÜ-4-hydroxy-2-metho xy-3,4,5,6-tetrahydro-2H-pyran or a mixture thereof; the compounds are anti-atherosclerotic agents.

IPC 1-7

A61K 31/415; C07D 405/12

IPC 8 full level

A61K 31/415 (2006.01); A61P 9/10 (2006.01); C07D 405/12 (2006.01); C07F 7/18 (2006.01)

CPC (source: EP US)

A61P 9/10 (2017.12 - EP); C07D 405/12 (2013.01 - EP US); C07F 7/1804 (2013.01 - EP US)

Citation (search report)

  • [A] EP 0043788 A1 19820113 - SCHERING AG [DE]
  • [A] EP 0252476 A2 19880113 - WARNER LAMBERT CO [US]
  • [A] US 4160666 A 19790710 - MCCABE JOHN M, et al
  • [A] DE 2635876 A1 19770303 - DU PONT
  • [A] CHEMICAL ABSTRACTS, vol. 103, no. 11, September 16, 1985 Columbus, Ohio, USA SHARPE, THOMAS R. et al. "Preparation, antiarthritic and analgesic activity of 4,5-diaryl-2-(substituted thio)-1H-imidazoles and their sulfoxides and sul- fones." page 603, column 2, abstract -no. 87 810f
  • [A] CHEMICAL ABSTRACTS, vol. 102, no. 5, February 4, 1985 Columbus, Ohio, USA ABRAMOVA N. D. et al. "Alkylation of azole thio- nes." page 566, column 2, abstract -no. 45 836t

Designated contracting state (EPC)

AT BE CH DE DK ES FR GB GR IT LI LU NL SE

DOCDB simple family (publication)

EP 0391796 A1 19901010; CA 2013845 A1 19901005; GB 8907656 D0 19890517; JP H03115280 A 19910516; US 5006546 A 19910409

DOCDB simple family (application)

EP 90400918 A 19900404; CA 2013845 A 19900404; GB 8907656 A 19890405; JP 8843790 A 19900404; US 49862890 A 19900326