EP 0391892 A1 19901017 - NONGLYCOSYLATED ANALOGS OF HUMAN COLONY STIMULATING FACTORS.
Title (en)
NONGLYCOSYLATED ANALOGS OF HUMAN COLONY STIMULATING FACTORS.
Title (de)
NONGLYCOSYLIERTE ANALOGE VON MENSCHLICHEN KOLONIESTIMULIERENDEN FAKTOREN.
Title (fr)
ANALOGUES NON GLYCOSYLES DE FACTEURS HUMAINS DE STIMULATION DE COLONIES.
Publication
Application
Priority
US 8702799 W 19871030
Abstract (en)
[origin: WO8903881A1] An analog human colony stimulating factor (hCSF) is disclosed, comprising a mutant amino acid sequence which is substantially homologous to the native sequence of an hCSF having at least one N-glycosylation site, wherein the mutant sequence comprises at least one amino acid substitution, deletion or insertion inactivating the N-glycosylation site.
Abstract (fr)
Est décrit un facteur humain analogue de stimulation de colonie, comprenant une séquence d'amino acides mutante sensiblement semblable à la séquence native d'un hCSF (facteur de stimulation de colonie humain) ayant au moins un site de N-glycosylation, dans lequel la séquence mutante comprend au moins une substitution, une délétion ou une insertion d'amino acide, rendant inactif le site de N-glycosylation.
IPC 1-7
IPC 8 full level
C07K 14/00 (2006.01); C07K 14/52 (2006.01); C07K 14/53 (2006.01); C07K 14/535 (2006.01); C12N 1/19 (2006.01); C12N 15/09 (2006.01); C12P 21/02 (2006.01); C12R 1/865 (2006.01)
CPC (source: EP)
C07K 14/535 (2013.01)
Designated contracting state (EPC)
AT BE CH DE FR GB IT LI LU NL SE
DOCDB simple family (publication)
WO 8903881 A1 19890505; EP 0391892 A1 19901017; EP 0391892 A4 19901128; JP H03502322 A 19910530
DOCDB simple family (application)
US 8702799 W 19871030; EP 87907559 A 19871030; JP 50703087 A 19871030