EP 0406659 A1 19910109 - Substituted 3-aminosydnonimines, process for their preparation and their use.
Title (en)
Substituted 3-aminosydnonimines, process for their preparation and their use.
Title (de)
Substituierte 3-Aminosydnonimine, Verfahren zu ihrer Herstellung und ihre Verwendung.
Title (fr)
3-aminosydnonimines substituées, procédé pour leur préparation et leur utilisation.
Publication
Application
Priority
DE 3921796 A 19890703
Abstract (en)
[origin: CA2020217A1] Ref.3432 Dr.Eu/L10765 Substituted 3-aminosydnone imines of the formula I (I) and their pharmacologically acceptable acid addition salts, in which R1 denotes e.g. hydrogen; R2 denotes e.g. an alkyl radical; at least two of the radicals R3, R4, R5 and R6 denote alkyl radicals and the others denote hydrogen, are prepared by cyclization of a compound of the formula II (II) and, if appropriate, subsequent acylation, and have useful pharmacological properties.
Abstract (de)
Substituierte 3-Aminosydnonimine der Formel I <IMAGE> und ihre pharmakologisch annehmbaren Säureadditionssalze, worin R¹ z.B. Wasserstoff; R² z.B. einen Alkylrest; mindestens zwei der Reste R³, R<4>, R<5>, R<6> Alkylreste und die anderen Wasserstoff bedeuten, werden durch Cyclisierung einer Verbindung der Formel II <IMAGE> und gegebenenfalls anschließende Acylierung hergestellt und besitzen wertvolle pharmakologische Eigenschaften.
IPC 1-7
IPC 8 full level
A61K 31/445 (2006.01); A61P 9/08 (2006.01); A61P 9/10 (2006.01); A61P 9/12 (2006.01); C07D 271/04 (2006.01); C07D 413/04 (2006.01)
CPC (source: EP KR US)
A61P 9/08 (2017.12 - EP); A61P 9/10 (2017.12 - EP); A61P 9/12 (2017.12 - EP); C07D 271/04 (2013.01 - EP US); C07D 413/04 (2013.01 - KR)
Citation (search report)
- [A] EP 0312773 A2 19890426 - CASSELLA FARBWERKE MAINKUR AG [DE]
- [A] EP 0023343 A2 19810204 - CASSELLA FARBWERKE MAINKUR AG [DE]
- [AD] DE 1695897 A1 19720203 - TAKEDA CHEMICAL INDUSTRIES LTD [JP]
- [A] DE 1670127 A1 19701203 - BOEHRINGER SOHN INGELHEIM
- [A] EP 0210474 A1 19870204 - CASSELLA FARBWERKE MAINKUR AG [DE]
- [AP] EP 0324408 A1 19890719 - CASSELLA FARBWERKE MAINKUR AG [DE]
- [A] DE 2131826 A1 19720105 - SANDOZ AG
- [A] DE 2126035 A1 19711209
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB IT LI NL SE
DOCDB simple family (publication)
EP 0406659 A1 19910109; CA 2020217 A1 19910104; CZ 329690 A3 19930317; DD 297410 A5 19920109; DE 3921796 A1 19910117; HU 904062 D0 19901228; HU T58731 A 19920330; JP H0344391 A 19910226; KR 910002848 A 19910226; US 5179206 A 19930112; ZA 905147 B 19910424
DOCDB simple family (application)
EP 90112003 A 19900625; CA 2020217 A 19900629; CS 329690 A 19900702; DD 34243190 A 19900702; DE 3921796 A 19890703; HU 406290 A 19900702; JP 17036290 A 19900629; KR 900009911 A 19900702; US 53483290 A 19900607; ZA 905147 A 19900702