EP 0418292 A4 19910925 - PHOSPHORAMIDES USEFUL AS ANTITUMOR AGENTS
Title (en)
PHOSPHORAMIDES USEFUL AS ANTITUMOR AGENTS
Publication
Application
Priority
US 19840888 A 19880525
Abstract (en)
[origin: WO8911484A1] An antitumor compound of formula (I), wherein R1 and R2 may be the same or different and are selected from the group consisting of hydrogen or lower alkyl which is non-substituted with halo, hydroxy or lower alkoxy, provided that the substituent is not on the -carbon; or R1 and R2 taken together with the nitrogen to which they are attached form a morpholion ring. R is a nitro-substituted aryl or nitro-substituted nitrogen, sulfur or oxygen containing heteroaromatic groups R3 and R4 are each independently hydrogen, an electron withdrawing group or lower alkyl which is unsubstituted or mono-substituted with alkyl or an electron withdrawing group.
IPC 1-7
IPC 8 full level
A61K 31/685 (2006.01); A61P 35/00 (2006.01); C07F 9/24 (2006.01); C07F 9/572 (2006.01); C07F 9/58 (2006.01); C07F 9/6506 (2006.01); C07F 9/6533 (2006.01)
CPC (source: EP)
A61P 35/00 (2017.12); C07F 9/2429 (2013.01); C07F 9/2458 (2013.01); C07F 9/6506 (2013.01)
Citation (search report)
- [A] CH 372051 A 19630930 - ASTA WERKE AG CHEM FAB [DE]
- See references of WO 8911484A1
Designated contracting state (EPC)
AT BE CH DE FR GB IT LI LU NL SE
DOCDB simple family (publication)
WO 8911484 A1 19891130; EP 0418292 A1 19910327; EP 0418292 A4 19910925; JP H04501253 A 19920305
DOCDB simple family (application)
US 8902299 W 19890525; EP 89906634 A 19890525; JP 50640089 A 19890525