EP 0423312 A4 19910828 - DETECTION OF ENDOTOXIN IN PHARMACEUTICAL PREPARATIONS BY MASS SPECTROMETRY
Title (en)
DETECTION OF ENDOTOXIN IN PHARMACEUTICAL PREPARATIONS BY MASS SPECTROMETRY
Publication
Application
Priority
US 34748589 A 19890504
Abstract (en)
[origin: WO9013534A1] The present invention relates to a method of detection of endotoxin in polypeptide compositions. In particular, this invention contemplates a method for measuring endotoxin by quantitating the amount of a volatile derivatized component of endotoxin, beta-hydroxymyristic acid, present in polypeptide compositions. The present invention can be used for testing the endotoxin content of products which are intended for use in clinical medicine, including those produced by recombinant DNA technology.
IPC 1-7
IPC 8 full level
G01N 27/62 (2006.01); G01N 30/06 (2006.01); G01N 30/88 (2006.01); G01N 33/579 (2006.01); G01N 33/68 (2006.01)
CPC (source: EP)
G01N 33/68 (2013.01); G01N 33/6842 (2013.01)
Citation (search report)
- [Y] PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE USA, vol. 75, no 8, August 1978, pages 3993-3997, Washington, DE, US; S.K. MAITRA et al. "Determination of lipid A and endotoxin in serum by mass spectroscopy"
- See references of WO 9013534A1
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB IT LI LU NL SE
DOCDB simple family (publication)
WO 9013534 A1 19901115; AU 5641990 A 19901129; CA 2032133 A1 19901105; EP 0423312 A1 19910424; EP 0423312 A4 19910828; JP H04501315 A 19920305
DOCDB simple family (application)
US 9002459 W 19900503; AU 5641990 A 19900503; CA 2032133 A 19900503; EP 90907628 A 19900503; JP 50756990 A 19900503