EP 0431060 A4 19910925 - METHOD OF CATALYZING STEREOCHEMICAL REACTIONS
Title (en)
METHOD OF CATALYZING STEREOCHEMICAL REACTIONS
Publication
Application
Priority
US 23730588 A 19880826
Abstract (en)
[origin: WO9002192A1] A method for increasing the rate of a chemical reaction involving conversion of at least one reactant to at least one product which comprises contacting the reactant with at least one appropriate monoclonal antibody to the reactant under suitable conditions permitting formation of a complex between the monoclonal antibody and the reactant, conversion of the reactant to the product and release of the product from the complex, the monoclonal antibody being characterized by a K > 1, where K = kr/kp, kr is the affinity constant of the monoclonal antibody for the reactant and kp is the affinity constant of the monoclonal antibody for the product, by an r1 > ro, where r1 is the rate of formation of the complex between the antibody and the reactant and where ro is the rate of the chemical reaction in the absence of monoclonal antibody, by an r2 > ro, where r2 is the rate of the conversion of the complexed reactant to the complexed product and by an r3 > ro, where r3 is the rate of release of the product from the complex.
IPC 1-7
C12P 1/00; C12P 19/00; C12P 19/02; C12N 9/00; C12N 9/16; C12N 9/38
IPC 8 full level
B01J 31/06 (2006.01); C07K 16/42 (2006.01); C07K 16/44 (2006.01); C12N 5/10 (2006.01); C12N 9/00 (2006.01); C12N 15/02 (2006.01); C12N 15/09 (2006.01); C12P 1/00 (2006.01); C12P 13/22 (2006.01); C12P 17/10 (2006.01); C12P 19/02 (2006.01); C12P 19/34 (2006.01); C12P 21/08 (2006.01); C12P 41/00 (2006.01); C12R 1/91 (2006.01)
CPC (source: EP)
C07K 16/4241 (2013.01); C07K 16/44 (2013.01); C12N 9/0002 (2013.01); C12P 1/00 (2013.01); C12P 13/227 (2013.01); C12P 17/10 (2013.01); C12P 19/34 (2013.01); C12P 41/004 (2013.01)
Citation (search report)
- [X] WO 8502414 A1 19850606 - IGEN INC [US]
- [XP] WO 8809380 A1 19881201 - SCRIPPS CLINIC RES [US]
- [X] JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 110, no. 16, 3rd August 1988, pages 5593-5594, American Chemical Society; D. HILVERT et al.: "Stereospecific claisen rearrangement catalyzed by an antibody"
- See references of WO 9002192A1
Designated contracting state (EPC)
AT BE CH DE FR GB IT LI LU NL SE
DOCDB simple family (publication)
WO 9002192 A1 19900308; AU 4195693 A 19931007; AU 4213289 A 19900323; AU 657864 B2 19950323; EP 0431060 A1 19910612; EP 0431060 A4 19910925; IL 91397 A0 19900429; JP H04501656 A 19920326; ZA 896408 B 19910529
DOCDB simple family (application)
US 8903696 W 19890825; AU 4195693 A 19930714; AU 4213289 A 19890825; EP 89910248 A 19890825; IL 9139789 A 19890823; JP 50936989 A 19890825; ZA 896408 A 19890822