EP 0442424 B1 19941221 - Treatment of sleep apneas with azapirone derivatives.
Title (en)
Treatment of sleep apneas with azapirone derivatives.
Title (de)
Behandlung von Schlaf-Apnoea mit Azapironderivaten.
Title (fr)
Traitement des apnées de sommeil avec des dérivés azapirones.
Publication
Application
Priority
US 47882090 A 19900212
Abstract (en)
[origin: EP0442424A1] Azarpirone derivatives of the formulas I and II are useful in the treatment of sleep apneas. <CHEM> Z is a member selected from the group <CHEM> with R<3> and R<4> being independently selected from C1-4 alkyl and hydrogen. A can be -CH2-, -O-, -CH2CH2- or -CH=CH-. The dotted and solid line represents either a single or a double chemical bond. <CHEM>
IPC 1-7
IPC 8 full level
A61K 31/435 (2006.01); A61K 31/438 (2006.01); A61K 31/505 (2006.01); A61K 31/506 (2006.01); A61P 11/16 (2006.01); A61P 25/00 (2006.01); C07D 403/12 (2006.01); C07D 405/12 (2006.01); C07D 417/12 (2006.01); C07D 491/08 (2006.01)
CPC (source: EP KR)
A61K 31/435 (2013.01 - EP); A61K 31/505 (2013.01 - EP KR); A61P 11/16 (2017.12 - EP); A61P 25/00 (2017.12 - EP)
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IT LI LU NL SE
DOCDB simple family (publication)
EP 0442424 A1 19910821; EP 0442424 B1 19941221; AT E115858 T1 19950115; CA 2036039 A1 19910813; CY 1990 A 19970905; DE 69106008 D1 19950202; DE 69106008 T2 19950504; DK 0442424 T3 19950220; ES 2068407 T3 19950416; HK 19797 A 19970220; HU 910437 D0 19910828; HU T56497 A 19910930; IL 97053 A0 19920329; IL 97053 A 19951031; JP 3227578 B2 20011112; JP H0517358 A 19930126; KR 910015301 A 19910930
DOCDB simple family (application)
EP 91101889 A 19910211; AT 91101889 T 19910211; CA 2036039 A 19910208; CY 199097 A 19970905; DE 69106008 T 19910211; DK 91101889 T 19910211; ES 91101889 T 19910211; HK 19797 A 19970220; HU 43791 A 19910211; IL 9705391 A 19910125; JP 3902991 A 19910212; KR 910002289 A 19910211