EP 0444068 A1 19910904 - TRIALKYSILYL ESTERS OF AMINO ACIDS AND THEIR USE IN THE SYNTHESIS OF PEPTIDES.
Title (en)
TRIALKYSILYL ESTERS OF AMINO ACIDS AND THEIR USE IN THE SYNTHESIS OF PEPTIDES.
Title (de)
TRIALKYLSILYL-AMINOSÄUREESTER UND DEREN VERWENDUNG BEI DER PEPTIDHERSTELLUNG.
Title (fr)
TRIALKYLSILYLE ESTERS D'ACIDES AMINES ET LEUR EMPLOI DANS LA SYNTHESE DE PEPTIDES.
Publication
Application
Priority
GB 8827083 A 19881119
Abstract (en)
[origin: WO9005738A1] A novel procedure is described for synthesising peptides in which successive amino acids are attached to an incipient polypetide chain by addition of a carboxy-protected amino acid to the carboxy end of said chain. The procedure involves the use of silyl esters of amino acids, many of which are novel and form a further aspect of the invention.
Abstract (fr)
L'invention concerne un nouveau procédé de synthèse de peptides, dans lequel on fixe des acides aminés successifs à une chaîne de polypeptides naissante par addition d'un acide aminé à protection carboxy à l'extrémité carboxy de ladite chaîne. Le procédé met en oeuvre l'emploi de silyle esters d'acides aminés, dont beaucoup sont nouveaux et constituent un autre aspect de l'invention.
IPC 1-7
IPC 8 full level
C07F 7/18 (2006.01); C07K 1/04 (2006.01); C07K 1/06 (2006.01); C07K 1/08 (2006.01)
CPC (source: EP)
C07K 1/04 (2013.01); C07K 1/088 (2013.01)
Citation (search report)
See references of WO 9005738A1
Designated contracting state (EPC)
AT BE CH DE FR GB IT LI LU NL SE
DOCDB simple family (publication)
WO 9005738 A1 19900531; AU 4517289 A 19900612; CA 2003308 A1 19900519; EP 0444068 A1 19910904; FI 912411 A0 19910517; GB 8827083 D0 19881221; HU 896580 D0 19910828; HU T58106 A 19920128; IL 92338 A0 19900726; JP H04502908 A 19920528; ZA 898774 B 19900829
DOCDB simple family (application)
GB 8901350 W 19891115; AU 4517289 A 19891115; CA 2003308 A 19891117; EP 89912478 A 19891115; FI 912411 A 19910517; GB 8827083 A 19881119; HU 658089 A 19891115; IL 9233889 A 19891117; JP 51170289 A 19891115; ZA 898774 A 19891117