Global Patent Index - EP 0444156 A4

EP 0444156 A4 19921209 - METHOD FOR TREATING VASCULAR DISEASES

Title (en)

METHOD FOR TREATING VASCULAR DISEASES

Publication

EP 0444156 A4 19921209 (EN)

Application

EP 90901238 A 19891120

Priority

US 27515188 A 19881121

Abstract (en)

[origin: WO9005531A1] The present invention relates to the use of renin inhibitors and to renin inhibitor compositions for treating, inhibiting, relieving or reversing vascular diseases including those vascular diseases associated with functional and/or biochemical abnormalities, and in particular peripheral vascular diseases and microvascular diseases associated with diabetes, especially diabetic retinopathy, diabetic nephropathy and diabetic neuropathy.

IPC 1-7

A61K 37/00

IPC 8 full level

C07D 211/76 (2006.01); A61K 38/00 (2006.01); A61K 38/55 (2006.01); A61K 45/00 (2006.01); A61P 3/08 (2006.01); A61P 13/02 (2006.01); A61P 15/00 (2006.01); A61P 27/02 (2006.01); C07D 211/46 (2006.01); C07D 417/04 (2006.01); C07D 417/06 (2006.01); C07D 417/14 (2006.01); C07K 5/02 (2006.01); C07K 5/078 (2006.01)

CPC (source: EP)

A61K 38/005 (2013.01); A61P 3/08 (2017.12); A61P 13/02 (2017.12); A61P 15/00 (2017.12); A61P 27/02 (2017.12); C07D 211/46 (2013.01); C07D 417/06 (2013.01); C07D 417/14 (2013.01); C07K 5/0227 (2013.01); C07K 5/06139 (2013.01)

Citation (search report)

  • [X] DE 3626130 A1 19880211 - MERCK PATENT GMBH [DE]
  • EP 1610588 A2 20051228 - BOSE CORP [US]
  • [X] EP 0161588 A2 19851121 - MERCK PATENT GMBH [DE]
  • [X] EP 0179352 A2 19860430 - MERCK PATENT GMBH [DE]
  • [X] EP 0272444 A2 19880629 - MERCK PATENT GMBH [DE]
  • [Y] ENDOCRINOL. JPN., vol. 30, no. 2, April 1983, pages 147-153, JP; N. SHIMOJO: "Plasma inactive renin in patients with diabetes mellitus: effects of standing and the relation to serum protease inhibitor"
  • [Y] HYPERTENSION, vol. 12, no. 3, September 1988, page 341, US; M. BURSZTYN et al.: "Dissociation between plasma renin inhibition and blood pressure response to a renin inhibitor in hypertensive patients", (Council for high blood pressure research; 42nd Annual fall conference and scientific sessions, San Francisco, California, September 1988)
  • [Y] HYPERTENSION, vol. 12, no. 3, September 1988, page 360, US; A. DELABAYS et al.: "Effects of a new renin inhibitor (ABBOTT-64662) in normal volunteers", (Council for high blood pressure research; 42nd Annual fall conference and scientific sessions, San Francisco, California, September 1988)
  • [Y] JOURNAL OF NARA MEDICAL ASSOCIATION, vol. 35, no. 1, 29th February 1984, pages 59-75; T. HIJIOKA: "Studies on the inhibitory effect of serine protease inhibitors/in human blood on trypsin-activated plasma prorenin; with special reference to hemodialyzed patients with diabetic nephropathy"
  • [Y] KLINISCHE WOCHEN-SCHRIFT, vol. 66, no. 18, 15th September 1988, pages 883-891, DE; J. MANN et al.: "Renin-Angiotensin System beim diabetischen Patienten"
  • [Y] THE AMERICAN JOURNAL OF CARDIOLOGY, vol. 37, no. 4, 31st March 1976, pages 667-674, US; R.P. DAY et al.: "Big renin: identification, chemical properties and clinical implications"
  • See references of WO 9005531A1

Designated contracting state (EPC)

BE CH DE ES FR GB IT LI NL SE

DOCDB simple family (publication)

WO 9005531 A1 19900531; CA 2003382 A1 19900521; EP 0444156 A1 19910904; EP 0444156 A4 19921209; GR 1001145 B 19930524; GR 890100773 A 19901231

DOCDB simple family (application)

US 8905248 W 19891120; CA 2003382 A 19891120; EP 90901238 A 19891120; GR 890100773 A 19891121