Global Patent Index - EP 0456758 A4

EP 0456758 A4 19920708 - ANAPHYLATOXIN-RECEPTOR LIGANDS

Title (en)

ANAPHYLATOXIN-RECEPTOR LIGANDS

Publication

EP 0456758 A4 19920708 (EN)

Application

EP 90903567 A 19900116

Priority

US 30469389 A 19890131

Abstract (en)

[origin: WO9009162A2] Oligopeptide compounds or oligopeptide analogue compounds of the formula A-B-D-E-G-J-L-M-Q-T are ligands for the anaphylatoxin receptor and are useful in the treatment of inflammatory disease states. Also disclosed are anaphylatoxin receptor ligand compositions and a method for modulating anaphylatoxin activity.

IPC 1-7

C07K 7/00; A61K 37/00; C07C 229/22

IPC 8 full level

A61K 38/00 (2006.01); A61P 37/00 (2006.01); C07D 211/60 (2006.01); C07D 327/08 (2006.01); C07D 487/04 (2006.01); C07D 513/04 (2006.01); C07K 5/10 (2006.01); C07K 7/02 (2006.01); C07K 7/06 (2006.01); C07K 14/47 (2006.01)

CPC (source: EP)

A61P 37/00 (2017.12); C07K 7/02 (2013.01); C07K 14/472 (2013.01); A61K 38/00 (2013.01)

Citation (search report)

  • [Y] US 4692511 A 19870908 - HAHN GARY S [US]
  • [Y] BIOCHEMISTRY, vol. 23, no. 4, 14th February 1984, pages 585-588, American Chemical Society; C.G. UNSON et al.: "Active site of C3a anaphylatoxin: contributions of the lipophilic and orienting residues"
  • [Y] PROC. NATL. ACAD. SCI. USA, vol. 86, no. 1, January 1989, pages 292-296; K.W. MOLLISON et al.: "Identification of receptor-binding residues in the inflammatory complement protein C5a by site-directed mutagenesis"
  • [Y] B. WEINSTEIN: "Chemistry and Biochemistry of Amino Acids, Peptides, and Proteins. A Survey of recent Developments", vol. 7, 1983, pages 267-349, Marcel Dekker, Inc.; Chapter 5, A.F. SPATOLA: "Peptide backbone modifications: a structure-acitivity analysis of peptides containing amide bond surrogates"
  • See references of WO 9009162A2

Designated contracting state (EPC)

AT BE CH DE DK ES FR GB IT LI LU NL SE

DOCDB simple family (publication)

WO 9009162 A2 19900823; WO 9009162 A3 19901129; CA 2045578 A1 19900801; EP 0456758 A1 19911121; EP 0456758 A4 19920708; GR 900100052 A 19910607; JP H04503073 A 19920604

DOCDB simple family (application)

US 9000296 W 19900116; CA 2045578 A 19900116; EP 90903567 A 19900116; GR 900100052 A 19900130; JP 50368690 A 19900116