EP 0456760 A1 19911121 - LIPOXYGENASE INHIBITING COMPOUNDS.
Title (en)
LIPOXYGENASE INHIBITING COMPOUNDS.
Title (de)
LIPOXYGENASE INHIBIERENDE VERBINDUNG.
Title (fr)
COMPOSES INHIBITEURS DE LIPOXYGENASE.
Publication
Application
Priority
US 30532189 A 19890201
Abstract (en)
[origin: WO9008545A1] Certain N-aryl-, N-heteroaryl-, N-arylalkyl-, N-heteroarylalkyl-, N-arylcyclopropyl- and N-heteroaryl-cyclopropyl-N'-hydroxyurea compounds are inhibitors of lipoxygenase enzyme activity and are thus useful agents in treating disease states such as asthma, arthritis, allergy, psoriasis, inflammatory bowel disease, gout, adult respiratory distress syndrome, endotoxin shock, and other inflammatory conditions in which the products of the arachidonic acid cascade are implicated.
Abstract (fr)
Certains composés N-aryle-, N-hétéroaryle, N-arylalcoyle-, N-hétéroarylalcoyle-, N-arylcyclopropyle- et N-hétéroarylcyclopropyle-n'-hydroxyurée sont des inhibiteurs de l'activité de l'enzyme de lipoxygénase, et sont par conséquent des agents utiles dans le traitement d'états pathologiques tels que l'asthme, l'arthrite, les allergies, le psoriasis, des affections intestinales inflammatoires, la goutte, le syndrome de souffrance respiratoire chez l'adulte, le choc de l'endotoxine, ainsi que d'autres états inflammatoires dans lesquels les produits de la cascade de l'acide arachidonique sont impliqués.
IPC 1-7
IPC 8 full level
A61K 31/17 (2006.01); A61K 31/215 (2006.01); A61K 31/34 (2006.01); A61K 31/341 (2006.01); A61K 31/343 (2006.01); A61K 31/38 (2006.01); A61K 31/381 (2006.01); A61K 31/40 (2006.01); A61K 31/403 (2006.01); A61K 31/404 (2006.01); A61P 37/06 (2006.01); A61P 43/00 (2006.01); C07C 275/64 (2006.01); C07D 207/09 (2006.01); C07D 209/14 (2006.01); C07D 213/30 (2006.01); C07D 213/68 (2006.01); C07D 307/42 (2006.01); C07D 307/52 (2006.01); C07D 307/81 (2006.01); C07D 333/16 (2006.01); C07D 333/20 (2006.01); C07D 333/32 (2006.01); C07D 333/56 (2006.01); C07D 333/58 (2006.01); C07D 333/64 (2006.01); C07D 405/04 (2006.01); C07D 405/06 (2006.01); C07D 409/04 (2006.01); C07D 409/06 (2006.01)
CPC (source: EP)
A61P 37/06 (2017.12); A61P 43/00 (2017.12); C07C 275/64 (2013.01); C07D 209/14 (2013.01); C07D 213/30 (2013.01); C07D 213/68 (2013.01); C07D 307/42 (2013.01); C07D 307/52 (2013.01); C07D 307/81 (2013.01); C07D 333/16 (2013.01); C07D 333/20 (2013.01); C07D 333/32 (2013.01); C07D 333/56 (2013.01); C07D 333/58 (2013.01); C07D 333/64 (2013.01); C07D 405/06 (2013.01); C07D 409/04 (2013.01); C07D 409/06 (2013.01); C07C 2601/02 (2017.04)
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB IT LI LU NL SE
DOCDB simple family (publication)
WO 9008545 A1 19900809; CA 2046872 A1 19900802; EP 0456760 A1 19911121; EP 0456760 A4 19920108; GR 900100060 A 19910628; JP H04503074 A 19920604
DOCDB simple family (application)
US 9000376 W 19900125; CA 2046872 A 19900125; EP 90903687 A 19900125; GR 900100060 A 19900201; JP 50369390 A 19900125