EP 0460418 A2 19911211 - Novel Dihydropyridine derivative.
Title (en)
Novel Dihydropyridine derivative.
Title (de)
Dihydropyridin-Derivate.
Title (fr)
Dérivés de dihydropyridine.
Publication
Application
Priority
JP 11712990 A 19900507
Abstract (en)
(I) <CHEM> wherein R1 represents a lower alkyl group which may or may not have a substituent group, a lower cycloalkyl group which may or may not have a substituent group, a lower alkenyl group which may or may not have a substituent group, a lower alkynyl group which may or may not have a substituent group, or 3,4-dihydro-2H-benzo[b]pyran-4-yl group which may or may not have a substituent group; R<2> and R<3>, which may or may not be the same, independently represent a lower alkyl group which may or may not have a substituent group, amino group or a cyano group; X represents an aryl group which may or may not have a substituent group, or an unsaturated heterocyclic group which may or may not have a substituent group; and Y represents a 3,4-dihydro-2H-benzo[b]pyran-4-yl group which may or may not have a substituent group; and salts thereof. They have extremely strong, slow and long-acting vasodilating action and antihypertensive action with less adverse effects so that they are useful as therapeutic agents for cardiovascular diseases.
IPC 1-7
IPC 8 full level
C07D 405/12 (2006.01); A61K 31/44 (2006.01); A61K 31/443 (2006.01); A61K 31/4433 (2006.01); A61P 9/00 (2006.01); A61P 9/08 (2006.01); A61P 9/12 (2006.01); C07D 405/04 (2006.01); C07D 405/14 (2006.01); C07D 409/14 (2006.01); C07D 413/14 (2006.01)
CPC (source: EP US)
A61P 9/00 (2017.12 - EP); A61P 9/08 (2017.12 - EP); A61P 9/12 (2017.12 - EP); C07D 405/04 (2013.01 - EP US); C07D 405/14 (2013.01 - EP US); C07D 409/14 (2013.01 - EP US); C07D 413/14 (2013.01 - EP US)
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IT LI LU NL SE
DOCDB simple family (publication)
EP 0460418 A2 19911211; EP 0460418 A3 19911227; JP H0413679 A 19920117; US 5208245 A 19930504
DOCDB simple family (application)
EP 91107403 A 19910507; JP 11712990 A 19900507; US 69670491 A 19910507