EP 0467965 A1 19920129 - PLASMODIUM CIRCUMSPOROZOITE PROTEIN ANALOGS LACKING REPEAT SEQUENCES.
Title (en)
PLASMODIUM CIRCUMSPOROZOITE PROTEIN ANALOGS LACKING REPEAT SEQUENCES.
Title (de)
PLASMODIUM-CIRCUMSPOROZOIT-PROTEIN-ANALOGE AN WELCHEN WIEDERKEHRENDE SEQUENZEN FEHLEN.
Title (fr)
ANALOGUES DE PROTEINES DE CIRCUMSPOROZOITE DE PLASMODIUM AUXQUELS IL MANQUE DES SEQUENCES DE REPETITION.
Publication
Application
Priority
US 33628889 A 19890411
Abstract (en)
[origin: EP0392820A2] Recombinant immunogenic analogs of Plasmodium circumsporozoite (CS) proteins useful as malaria subunit vaccines which lack one or more of the repeat epitopes of the native CS protein but have at least one nonrepeat flanking epitope from each of the amino terminal and carboxy terminal flanking regions of the native CS protein.
Abstract (fr)
L'invention concerne des analogues immunogéniques de recombinaison de protéines de circumsporozoïte de plasmodium (CS), utiles comme vaccins de sous-unités du paludisme, auxquels il manque un ou plusieurs des épitopes de répétition de la protéine CS native, mais ayant au moins un épitope de bordure de non-répétition provenant de chacune des régions de bordure des terminaisons amino et des terminaisons carboxy de la protéine CS native.
IPC 1-7
A61K 39/00; C07H 15/12; C07H 17/00; C07K 3/00; C07K 15/00; C07K 17/00; C12N 5/00; C12P 21/00
IPC 8 full level
A61K 39/00 (2006.01); A61K 39/015 (2006.01); A61P 33/02 (2006.01); C07K 14/00 (2006.01); C07K 14/44 (2006.01); C07K 14/445 (2006.01); C07K 16/20 (2006.01); C12N 1/19 (2006.01); C12N 15/09 (2006.01); C12N 15/30 (2006.01); C12P 21/02 (2006.01); C12R 1/865 (2006.01)
CPC (source: EP)
A61P 33/02 (2018.01); C07K 16/205 (2013.01); A61K 39/00 (2013.01); Y02A 50/30 (2018.01)
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB IT LI LU NL SE
DOCDB simple family (publication)
EP 0392820 A2 19901017; EP 0392820 A3 19901227; AP 134 A 19910716; AP 9000176 A0 19900430; AU 5524290 A 19901105; AU 635265 B2 19930318; CA 2051432 A1 19901012; EP 0467965 A1 19920129; EP 0467965 A4 19920415; IL 94063 A0 19910131; JP H04506064 A 19921022; NZ 233255 A 19930225; PT 93721 A 19901120; WO 9011775 A1 19901018; ZA 902741 B 19910327
DOCDB simple family (application)
EP 90303907 A 19900411; AP 9000176 A 19900411; AU 5524290 A 19900411; CA 2051432 A 19900411; EP 90906626 A 19900411; IL 9406390 A 19900411; JP 50647590 A 19900411; NZ 23325590 A 19900409; PT 9372190 A 19900410; US 9001980 W 19900411; ZA 902741 A 19900410