Global Patent Index - EP 0473576 A4

EP 0473576 A4 19930310 - SHORT THERAPEUTIC DSRNA OF DEFINED STRUCTURE

Title (en)

SHORT THERAPEUTIC DSRNA OF DEFINED STRUCTURE

Publication

EP 0473576 A4 19930310 (EN)

Application

EP 89906635 A 19890519

Priority

US 8902172 W 19890519

Abstract (en)

[origin: WO9014090A1] The present invention relates to the induction of proteins and the activation of enzymes in the cells of living organisms, including human beings. According to the invention, long nucleic and complexes, such as the polyriboinosinate and polycytidylate complexes, are modified to yield short dsRNA of defined sequence. Said short dsRNAs of defined sequence retain the ability to induce proteins and activate enzymes but are not as toxic as long dsRNA.

IPC 1-7

A61K 31/70; C07H 19/067; A61K 37/66

IPC 8 full level

A61K 31/00 (2006.01); A61K 31/70 (2006.01); A61P 43/00 (2006.01); C07H 19/067 (2006.01); C07H 21/02 (2006.01); C12N 15/09 (2006.01); C12N 15/11 (2006.01)

CPC (source: EP)

A61K 31/70 (2013.01); A61P 43/00 (2017.12)

Citation (search report)

Designated contracting state (EPC)

AT BE CH DE FR GB IT LI LU NL SE

DOCDB simple family (publication)

WO 9014090 A1 19901129; DK 188991 D0 19911119; EP 0473576 A1 19920311; EP 0473576 A4 19930310; JP H04507083 A 19921210; NO 914529 D0 19911119; NO 914529 L 19920414

DOCDB simple family (application)

US 8902172 W 19890519; DK 188991 A 19911119; EP 89906635 A 19890519; JP 50363789 A 19890519; NO 914529 A 19911119