EP 0473698 B1 19940713 - METHOD OF PREPARING D-PROPOXYPHENE.
Title (en)
METHOD OF PREPARING D-PROPOXYPHENE.
Title (de)
VERFAHREN ZUR HERSTELLUNG VON D-PROPOXYPHEN.
Title (fr)
PROCEDE DE PREPARATION DE D-PROPOXYPHENE.
Publication
Application
Priority
- US 9002831 W 19900517
- US 35756489 A 19890526
Abstract (en)
[origin: WO9014331A1] D-propoxyphene can be prepared by reacting d-oxyphene and propionic anhydride. Preferably, an excess of propionic anhydride is used. The reaction easily proceeds at temperatures of 70 to 80 DEG C and produces yields exceeding 95 percent of theory. The free base d-propoxyphene can easily be converted in high yields to its hydrochloride or napsylate salts, both analgesics.
IPC 1-7
IPC 8 full level
C07C 213/06 (2006.01); C07C 219/22 (2006.01)
CPC (source: EP)
C07C 213/06 (2013.01); C07C 219/22 (2013.01)
Designated contracting state (EPC)
CH DE FR GB IT LI NL
DOCDB simple family (publication)
WO 9014331 A1 19901129; AU 5675190 A 19901218; CA 2057866 A1 19901127; CA 2057866 C 20020326; DE 69010686 D1 19940818; DE 69010686 T2 19950302; EP 0473698 A1 19920311; EP 0473698 B1 19940713
DOCDB simple family (application)
US 9002831 W 19900517; AU 5675190 A 19900517; CA 2057866 A 19900517; DE 69010686 T 19900517; EP 90908865 A 19900517