EP 0474849 B1 19950913 - METHODS FOR DETERMINING ANTIPHOSPHOLIPID ANTIBODIES.
Title (en)
METHODS FOR DETERMINING ANTIPHOSPHOLIPID ANTIBODIES.
Title (de)
VERFAHREN ZUR BESTIMMUNG VON ANTIPHOSPHOLIPID ANTIKÖRPERN.
Title (fr)
PROCEDES DE DETERMINATION DES ANTICORPS ANTIPHOSPHOLIPIDE.
Publication
Application
Priority
- AU PJ954990 A 19900406
- AU PK218690 A 19900907
- AU 9100127 W 19910404
Abstract (en)
[origin: US5344758A] A method for determining whether antiphospholipid antibodies are present in a sample is disclosed. The method comprises contacting the sample with a negatively charged phospholipid and with beta -2-glycoprotein-I or a homolog or analog thereof and determining whether any antiphospholipid antibodies have bound to the contacted phospholipid and beta -2-glycoprotein-I, wherein detection of binding of antiphospholipid antibodies to the phospholipid and beta -2-glycoprotein-I, is indicative that antiphospholipid antibodies are present in the sample. Also disclosed is a method for determining whether a negatively charged phospholipid is present in a sample, a kit for use in an assay for determining whether antiphospholipid antibodies are present in a sample, a kit for use in an assay for determining whether a negatively charged phospholipid is present in a sample, a method for determining whether antiphospholipid antibodies in a sample are antibodies to an autoimmune disease or antibodies to an infectious disease and a method for determining whether antiphospholipid antibodies to an autoimmune disease and antiphospholipid antibodies to an infectious disease are present in a sample.
IPC 1-7
IPC 8 full level
G01N 33/53 (2006.01); G01N 33/564 (2006.01); G01N 33/92 (2006.01)
CPC (source: EP US)
G01N 33/92 (2013.01 - EP US); Y10S 435/81 (2013.01 - EP US)
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IT LI LU NL SE
DOCDB simple family (publication)
WO 9115772 A1 19911017; AT E127925 T1 19950915; CA 2058769 A1 19911007; CA 2058769 C 19990302; DE 69112966 D1 19951019; DE 69112966 T2 19960215; EP 0474849 A1 19920318; EP 0474849 A4 19940330; EP 0474849 B1 19950913; ES 2079653 T3 19960116; JP H0688823 A 19940329; US 5344758 A 19940906
DOCDB simple family (application)
AU 9100127 W 19910404; AT 91907571 T 19910404; CA 2058769 A 19910404; DE 69112966 T 19910404; EP 91907571 A 19910404; ES 91907571 T 19910404; JP 10239793 A 19930428; US 77752191 A 19911206