EP 0477248 A1 19920401 - ALPHA ANOMER OLIGONUCLEOTIDE COMPOUNDS WHICH INHIBIT RETROVIRUS REPLICATION.
Title (en)
ALPHA ANOMER OLIGONUCLEOTIDE COMPOUNDS WHICH INHIBIT RETROVIRUS REPLICATION.
Title (de)
ALPHA-OLIGONUKLEOTID-VERBINDUNGEN ALS INHIBITOREN DER REPLIKATION VON RETROVIREN.
Title (fr)
COMPOSES OLIGONUCLEOTIDIQUES ANOMERES ALPHA INHIBANT LA REPLICATION DES RETROVIRUS.
Publication
Application
Priority
FR 8907782 A 19890613
Abstract (en)
[origin: WO9015813A1] The invention relates to oligonucleotide or oligodeoxynucleotide compounds with an alpha anomer structure and to their therapeutic applications. These compounds are used to inhibit RNA virus replication, in particular the alpha oligonucleotide d?5'(ACCGCGGGCTTGTCCCTG)?3' is used to inhibit the replication of AIDS virus HIV.
Abstract (fr)
L'invention concerne une application des composés oligonucléotidiques ou oligodésoxynucléotidiques à configuration anomérique alpha et leur application thérapeutique. Ces composés sont utilisés pour l'inhibition de la réplication des virus à ARN, plus particulièrement on utilise l'oligonucléotide alpha d5'(ACCGCGGGCTTGTCCCTG)3' à l'inhibition de la réplication du virus VIH du SIDA.
IPC 1-7
IPC 8 full level
A61K 31/70 (2006.01); A61P 31/12 (2006.01); A61P 31/18 (2006.01); C07H 21/00 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01); C12N 15/09 (2006.01); C12N 15/11 (2006.01); C12N 15/113 (2010.01)
CPC (source: EP)
A61K 31/70 (2013.01); A61P 31/12 (2017.12); A61P 31/18 (2017.12); C07H 21/00 (2013.01); C07H 21/04 (2013.01); C12N 15/1132 (2013.01); C12N 2310/337 (2013.01)
Citation (search report)
See references of WO 9015813A1
Designated contracting state (EPC)
CH DE ES FR GB IT LI
DOCDB simple family (publication)
WO 9015813 A1 19901227; EP 0477248 A1 19920401; FR 2648045 A1 19901214; FR 2648045 B1 19910927; JP H04506074 A 19921022
DOCDB simple family (application)
FR 9000412 W 19900612; EP 90909462 A 19900612; FR 8907782 A 19890613; JP 50892390 A 19900612