Global Patent Index - EP 0493434 A4

EP 0493434 A4 19930505 - TSH RECEPTOR

Title (en)

TSH RECEPTOR

Publication

EP 0493434 A4 19930505 (EN)

Application

EP 90913766 A 19900907

Priority

  • US 40489989 A 19890908
  • US 56566990 A 19900810

Abstract (en)

[origin: WO9103483A1] A protein having the biological activity of a mammalian TSH receptor, and purified nucleic acid encoding such a protein.

IPC 1-7

C07H 15/12; C12N 1/22; G01N 33/53; C07K 13/00

IPC 8 full level

C07K 14/575 (2006.01); C07K 14/00 (2006.01); C07K 14/705 (2006.01); C07K 14/72 (2006.01); C12N 1/21 (2006.01); C12N 15/09 (2006.01); C12N 15/16 (2006.01); C12P 21/02 (2006.01); G01N 33/53 (2006.01); C12R 1/91 (2006.01)

CPC (source: EP)

C07K 14/723 (2013.01)

Citation (search report)

  • [E] WO 9013643 A2 19901115 - GENENTECH INC [US]
  • [E] WO 9109121 A2 19910627 - HENNING BERLIN GMBH [DE]
  • [E] WO 9110735 A2 19910725 - INST NAT SANTE RECH MED [FR]
  • [E] WO 9109137 A1 19910627 - RAPOPORT BASIL [US]
  • [X] ACTA ENDOCRINOLOGICA, vol. 115, suppl. 281, 1987, pages 166-172, Copenhagen, DK; J. CHAN et al.: "TSH receptor structure"
  • [X] CLINICAL RESEARCH, vol. 29, no. 2, April 1981, page 294A, Thorofare, NJ, US; M.N. ISLAM et al.: "Purification of the human thyrotropin receptor"
  • [X] ENDOCRINOLOGY, vol. 110, no. 4, April 1982, pages 1381-1391, The Endocrine Soc., Baltimore, US; Y. KOIZUMI et al.: "Solubilisation, purification, and partial characterization of thyrotropin receptor from bovine and human thyroid glands"
  • [XP] SCIENCE, vol. 246, 22nd December 1989, pages 1620-1622, AAAS, Washington, DC, US; M. PARMENTIER et al.: "Molecular cloning of the thyroid receptor"
  • [XP] BIOCHEM. BIOPHYS. RES. COMMUN., vol. 165, no. 3, 29th December 1989, pages 1184-1190, Academic Press, New York, US; Y. NAGAYAMA et al.: "Molecular cloning, sequence and functional expression of the cDNA for the human thyrotropin receptor"
  • [XP] BIOCHEM. BIOPHYS. RES. COMMUN., vol. 165, no. 3, 29th December 1989, pages 1250-1255, Academic Press, New York, US; F. LIBERT et al.: "Cloning, sequencing and expression of the human thyrotropin (TSH) receptor: evidence for binding of autoantibodies"
  • [XP] 64TH MEETING OF THE AMERICAN THYROID ASSOCIATION, 1989, abstract no. T-51; L. FRAZIER-SEABROOK et al.: "Isolation of a thyroid-specific cDNA with over 80% aminoacid homology with the luteinizing hormone receptor"
  • See references of WO 9103483A1

Designated contracting state (EPC)

AT BE CH DE DK ES FR GB IT LI LU NL SE

DOCDB simple family (publication)

WO 9103483 A1 19910321; CA 2066263 A1 19910309; CA 2066263 C 19991102; EP 0493434 A1 19920708; EP 0493434 A4 19930505; JP 3181582 B2 20010703; JP H05501952 A 19930415

DOCDB simple family (application)

US 9005066 W 19900907; CA 2066263 A 19900907; EP 90913766 A 19900907; JP 51304090 A 19900907