Title (en)

Polypeptides and peptides, particularly recombinant polypeptides and peptides, nucleic acids coding for the same and use of these polypeptides and peptides in the diagnosis of tuberculosis.

Title (de)

Polypeptide und Peptide, insbesondere rekombinante Polypeptide und Peptide, dafür kodierende Nukleinsäuren und Verwendung dieser Polypeptide und Peptide in der Tuberkulosediagnose.

Title (fr)

Polypeptides et peptides, en particulier polypeptides et peptides recombinants, acides nucléiques les encodantes, et leur utilisation pour le diagnostic de la tuberculose.

Publication

EP 0499003 A1 19920819 (EN)

Application

EP 91400388 A 19910214

Priority

EP 91400388 A 19910214

Abstract (en)

The invention relates : to nucleic acids which contain particularly a nucleotide sequence extending from the extremity constituted by the nucleotide at position (1) to the extremity constituted by the nucleotide at position (149) represented on Figure 1, to the polypeptides coded by said nucleic acids. The polypeptides of the invention can be used for the diagnosis of tuberculosis, and can also be part of the active principle in the preparation of vaccine against tuberculosis. <IMAGE>

IPC 1-7

A61K 39/04; A61K 39/395; C12N 1/21; C12N 15/31; C12N 15/62; C12P 21/02; C12Q 1/68; G01N 33/569

IPC 8 full level

A61K 39/04 (2006.01); A61K 39/395 (2006.01); A61P 31/04 (2006.01); A61P 31/06 (2006.01); C07K 7/06 (2006.01); C07K 7/08 (2006.01); C07K 14/35 (2006.01); C07K 16/00 (2006.01); C07K 16/12 (2006.01); C12N 1/21 (2006.01); C12N 15/09 (2006.01); C12N 15/31 (2006.01); C12N 15/62 (2006.01); C12P 21/02 (2006.01); C12Q 1/68 (2006.01); C12Q 1/689 (2018.01); G01N 33/53 (2006.01); G01N 33/569 (2006.01); A61K 39/00 (2006.01); C12R 1/19 (2006.01)

CPC (source: EP US)

A61P 31/04 (2018.01 - EP); A61P 31/06 (2018.01 - EP); C07K 14/35 (2013.01 - EP US); C07K 16/1289 (2013.01 - EP US); C12Q 1/689 (2013.01 - EP US); A61K 39/00 (2013.01 - EP US); Y10S 435/975 (2013.01 - EP US)

Citation (search report)

• [Y] WO 9010701 A1 19900920 - COMMW SCIENT IND RES ORG [AU]
• [A] WO 9012875 A1 19901101 - INST NAT SANTE RECH MED [FR], et al
• [A] WO 8701118 A1 19870226 - SCRIPPS CLINIC RES [US]
• [Y] Infection and Immunity, Vol. 59, No. 1, January 1991, Washington, US, pages 372-382; S. NAGAI et al.: "Isolation and Partial Characterization of Major Protein Antigens in the Culture Fluid of Mycobacterium tuberculosis", Abstract; table 1.
• [Y] Journal of Bacteriology, Vol. 169, No. 3, March 1987, Baltimore, USA, pages 1080-1088; T.M. SHINNICK: "The 65-Kilodalton Antigen of Mycobacterium tuberculosis", Abstract.

Designated contracting state (EPC)

GB

DOCDB simple family (publication)

EP 0499003 A1 19920819; AT E153697 T1 19970615; AU 1223492 A 19920915; AU 659822 B2 19950601; CA 2104111 A1 19920815; CA 2104111 C 20080108; DE 69220042 D1 19970703; DE 69220042 T2 19971211; DE 69220042 T3 20051201; DK 0571420 T3 19971229; DK 0571420 T4 20050620; EP 0571420 A1 19931201; EP 0571420 B1 19970528; EP 0571420 B2 20050316; ES 2103928 T3 19971001; ES 2103928 T5 20050901; GR 3024408 T3 19971128; IL 100938 A0 19921115; JP H06504909 A 19940609; US 5955356 A 19990921; US 6638511 B1 20031028; WO 9214823 A1 19920903

DOCDB simple family (application)

EP 91400388 A 19910214; AT 92903939 T 19920207; AU 1223492 A 19920207; CA 2104111 A 19920207; DE 69220042 T 19920207; DK 92903939 T 19920207; EP 9200268 W 19920207; EP 92903939 A 19920207; ES 92903939 T 19920207; GR 970402052 T 19970811; IL 10093892 A 19920213; JP 50395292 A 19920207; US 10767693 A 19931004; US 29582099 A 19990421