EP 0499130 A1 19920819 - DC-89 derivatives.
Title (en)
DC-89 derivatives.
Title (de)
Derivate der Verbindung DC-89.
Title (fr)
Dérivés du composé DC-89.
Publication
Application
Priority
JP 2124391 A 19910215
Abstract (en)
DC-89 derivatives represented by the formula: <CHEM> wherein X represents chlorine or bromine; and R represents -SO2R<1> in which R<1> represents a straight-chain or branched alkyl group having 1 to 6 carbon atoms or phenyl group, or -CO(CH2)nR<2> in which n represents an integer of 0 to 5, and R<2> represents <CHEM> in which m represents an integer of 1 to 4; Y represents a single bond or CO; and Z represents CH2, O or N-R<3> (in which R<3> represents hydrogen or a straight-chain or branched alkyl group having 1 to 6 carbon atoms) or <CHEM> in which R<4> represents hydrogen or a straight-chain or branched alkyl group having 1 to 6 carbon atoms, and Ph represents phenyl group and pharmaceutically acceptable salts thereof have an excellent anti-tumor activity and are expected to be useful as anti-tumor compositions.
IPC 1-7
IPC 8 full level
C07D 487/04 (2006.01)
CPC (source: EP)
C07D 487/04 (2013.01)
Citation (search report)
- [AD] EP 0339681 A2 19891102 - MEIJI SEIKA KAISHA [JP]
- [AD] EP 0365041 A1 19900425 - KYOWA HAKKO KOGYO KK [JP]
- [AP] EP 0461603 A1 19911218 - KYOWA HAKKO KOGYO KK [JP]
Designated contracting state (EPC)
DE FR GB IT
DOCDB simple family (publication)
DOCDB simple family (application)
EP 92101913 A 19920205