EP 0505566 A1 19920930 - BIOSPECIFIC ANTIBODY TO CANCER CELL AND ENZYME WITH PRODRUG-ACTIVATING CHARACTERISTICS.
Title (en)
BIOSPECIFIC ANTIBODY TO CANCER CELL AND ENZYME WITH PRODRUG-ACTIVATING CHARACTERISTICS.
Title (de)
BIOSPEZIFISCHE ANTIKÖRPER GEGEN KREBSZELLEN UND ENZYME MIT WIRKSTOFFVORLÄUFER-AKTIVIERENDEN EIGENSCHAFTEN.
Title (fr)
ANTICORPS BIOSPECIFIQUE DES CELLULES CANCEREUSES ET ENZYME PRESENTANT DES CARACTERISTIQUES D'ACTIVATION PROMEDICAMENTEUSE.
Publication
Application
Priority
- JP 9732390 A 19900411
- JP 30160890 A 19901106
- JP 32654589 A 19891215
Abstract (en)
[origin: WO9109134A1] The present invention provides a hybrid monoclonal antibody having specificities against a human cancer cell and a prodrug-activating enzyme, a polydoma which produces said antibody and an anti-human-cancer-protein complex comprising said antibody and prodrug activating enzyme which is immunologically coupled thereto, and methods of using said antibody in combination with anticancer prodrug for therapy of cancer.
Abstract (fr)
La présente invention décrit un anticorps monoclonal hybride possédant des spécificités contre une cellule cancéreuse humaine et une enzyme d'activation promédicamenteuse, un polydome qui produit ledit anticorps et un complexe protéique anticancéreux renfermant ledit anticorps, et une enzyme d'activation promédicamenteuse qui y est immunologiquement couplée, ainsi que des procédés pour utiliser ledit anticorps en combinaison avec un promédicament anticancéreux destiné à la thérapie du cancer.
IPC 1-7
IPC 8 full level
A61K 47/48 (2006.01); C07K 16/46 (2006.01); C12P 21/08 (2006.01)
CPC (source: EP)
A61K 47/6879 (2017.07); A61K 47/6899 (2017.07); B82Y 5/00 (2013.01); C07K 16/468 (2013.01)
Citation (search report)
See references of WO 9109134A1
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IT LI LU NL SE
DOCDB simple family (publication)
WO 9109134 A1 19910627; CA 2069439 A1 19910616; EP 0505566 A1 19920930
DOCDB simple family (application)
JP 9001631 W 19901214; CA 2069439 A 19901214; EP 91900329 A 19901214