EP 0518933 A1 19921223 - LEUKAEMIA INHIBITORY FACTOR.
Title (en)
LEUKAEMIA INHIBITORY FACTOR.
Title (de)
LEUKÄMIE HEMMENDER FAKTOR.
Title (fr)
FACTEUR INHIBITEUR DE LA LEUCEMIE.
Publication
Application
Priority
GB 9004890 A 19900305
Abstract (en)
[origin: WO9113985A1] A substantially pure Leukaemia Inhibitory Factor (LIF) which is capable of associating with a mammalian extracellular matrix. Preferably, the N-terminal sequence comprises: NH2-U-arg-X-arg- where U is the residue of a peptide of 20 or fewer amino acids, or a covalent bond, and X is any amino acid. Such N-terminal sequences may also be attached to other proteins or peptides in order that they may become associated to the ECM.
Abstract (fr)
Facteur inhibiteur de la leucémie (LIF) pratiquement pur, capable de s'associer à une matrice extracellulaire de mammifère. De préférence, la séquence terminale N comprend: NH2-U-arg-X-arg- dans laquelle U est le résidu d'un peptide de 20 acides aminés ou moins, ou une liaison covalente, et X représente tout type d'acide aminé. Ces séquences terminales N peuvent également se relier à d'autres protéines ou peptides afin de s'associer à la matrice extracellulaire (ECM).
IPC 1-7
A61K 37/02; A61K 39/395; C07K 3/08; C07K 7/06; C07K 13/00; C12N 1/21; C12N 15/24; C12N 15/62; C12P 21/08
IPC 8 full level
A61K 38/00 (2006.01); A61K 38/22 (2006.01); A61K 39/395 (2006.01); A61P 1/02 (2006.01); A61P 7/00 (2006.01); A61P 25/00 (2006.01); A61P 35/02 (2006.01); A61P 43/00 (2006.01); C07K 1/107 (2006.01); C07K 7/06 (2006.01); C07K 14/00 (2006.01); C07K 14/435 (2006.01); C07K 14/54 (2006.01); C07K 16/00 (2006.01); C07K 16/24 (2006.01); C12N 1/21 (2006.01); C12N 5/10 (2006.01); C12N 15/09 (2006.01); C12N 15/24 (2006.01); C12N 15/62 (2006.01); C12P 21/02 (2006.01); C12P 21/08 (2006.01)
CPC (source: EP)
A61P 1/02 (2017.12); A61P 7/00 (2017.12); A61P 25/00 (2017.12); A61P 35/02 (2017.12); A61P 43/00 (2017.12); C07K 1/1075 (2013.01); C07K 7/06 (2013.01); C07K 14/54 (2013.01); C07K 16/244 (2013.01); C12N 15/62 (2013.01); C07K 2319/00 (2013.01)
Citation (search report)
See references of WO 9113985A1
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IT LI LU NL SE
DOCDB simple family (publication)
WO 9113985 A1 19910919; EP 0518933 A1 19921223; GB 9004890 D0 19900502; JP H05504955 A 19930729
DOCDB simple family (application)
GB 9100334 W 19910305; EP 91905515 A 19910305; GB 9004890 A 19900305; JP 50530291 A 19910305