Title (en)

CALCITONIN GENE RELATED PEPTIDE FOR THE TREATMENT OF UNDESCENDED TESTICLES

Publication

EP 0527774 A4 19930331 (EN)

Application

EP 91907817 A 19910410

Priority

AU PJ957390 A 19900410

Abstract (en)

[origin: WO9115246A1] Methods for the treatment of undescended testicles in male animals are described which methods comprise administering to a subject in need of such treatment calcitonin gene-related peptide (CGRP) or an analogue thereof having CGRP activity, optionally in association with a carrier and/or excipient, in an amount effective to cause testicular descent. There is also described pharmaceutical compositions for the treatment of undescended testicles in male animals, which comprise CGRP or an analogue thereof having CGRP activity in association with a pharmaceutically acceptable carrier and/or excipient. The use of CGRP in the treatment of undescended testicles is an effective alternative to invasive surgery.

IPC 1-7

A61K 37/30

IPC 8 full level

A61K 38/22 (2006.01); A61K 38/23 (2006.01); A61P 13/02 (2006.01); A61P 15/00 (2006.01)

CPC (source: EP)

A61K 38/225 (2013.01); A61P 13/02 (2017.12); A61P 15/00 (2017.12)

Citation (search report)

• [XP] WO 9012586 A1 19901101 - STIEF GEORG [DE]
• [X] WO 8502840 A1 19850704 - EVANS ROLAND M, et al
• [T] PEDIATRIC SURGERY vol. 6, no. 3, 1991, pages 176 - 179 S.L. LARKINS ET AL. 'LOCALISATION OF CALCITONIN GENE-RELATED PEPTIDE IMMUNOREACTIVITY WITHIN THE SPINAL NUCLEUS OF THE GENITOFEMORAL NERVE'
• [XP] JOURNAL OF PEDIATRIC SURGERY vol. 26, no. 5, May 1991, pages 615 - 617 W.-H. PARK ET AL. 'THE GUBERNACULUM SHOWS RHYTHMIC CONTRACTIBILITY AND ACTIVE MOVEMENT DURING TESTICULAR DESCENT'
• [Y] THE JOURNAL OF UROLOGY vol. 140, no. 5, 1988, pages 1191 - 1193 S.W. BEASLEY ET AL. 'THE ROLE OF THE GUBERNACULUM IN TESTICULAR DESCENT'
• [Y] AUSTRALIAN PAEDIATRIC JOURNAL vol. 23, no. 4, 1987, pages 215 - 216 J.M. HUTSON ET AL. 'ANNOTATION: THE MECHANISMS OF TESTICULAR DESCENT'
• [Y] BRAIN RESEARCH vol. 512, no. 2, 2 April 1990, pages 229 - 237 S. KAR ET AL. 'ORIGINS AND PROJECTIONS OF PEPTIDE-IMMUNOREACTIVE NERVES IN THE MALE RAT GENITOFEMORAL NERVE'
• [Y] JOURNAL OF PATHOLOGY vol. 154, no. 1-4, 1988, page 79A S. KAR ET AL. 'PRIMARY SENSORY NEURONES IMMUNOREACTIVE FOR CALCITONIN GENE-RELATED PEPTIDE (CGRP), GALANIN AND SUBSTANCE P AND CGRP-IMMUNOREACTIVE MOTORNEURONES CONSTITUTE THE MAJOR AFFERENT AND EFFERENT PEPTIDERGIC INPUT TO THE GENITOFEMORAL NERVE'
• See references of WO 9115246A1

Designated contracting state (EPC)

AT BE CH DE DK ES FR GB GR IT LI LU NL SE

DOCDB simple family (publication)

WO 9115246 A1 19911017; CA 2080354 A1 19911011; EP 0527774 A1 19930224; EP 0527774 A4 19930331; JP H05506223 A 19930916

DOCDB simple family (application)

AU 9100135 W 19910410; CA 2080354 A 19910410; EP 91907817 A 19910410; JP 50766891 A 19910410