Global Patent Index - EP 0530833 B1

EP 0530833 B1 19960417 - Process to prepare hard gelatine capsules containing chinese herbal extracts

Title (en)

Process to prepare hard gelatine capsules containing chinese herbal extracts

Title (de)

Verfahren zum Herstellen Hartgelatinekapseln, die chinesische Kräuterextrakte enthalten

Title (fr)

Procédé de préparation de capsules en gélatine dure contenant des extraits d'herbes chinoises

Publication

EP 0530833 B1 19960417 (EN)

Application

EP 92115192 A 19920904

Priority

JP 25274791 A 19910905

Abstract (en)

[origin: EP0530833A1] When a powdered extract of Kampo medicine is encapsulated as such in hard capsules, the pharmaceutical effects of the Kampo medicine cannot be fully achieved, since the dissolution of the content of the hard capsules requires a long period of time. Therefore, the present invention aims at providing Kampo medicine hard capsules having good dissolution properties. The present invention provides a process for producing Kampo medicine hard capsules which comprises compacting Kampo medicine extract powder, mixing magnesium stearate with the compacted Kampo medicine extract powder and filing the mixture into gelatin hard capsules. It is preferable that the weight ratio of the magnesium stearate to the Kampo medicine powdered extract ranges from 0.5/100 to 3/100. Furthermore, it is preferable that said Kampo medicine is selected from Oren-gedoku-to, Sho-saiko-to, Ninjin-to, San'o-shashin-to, Mao-bushi-saishin-to, Anchu-san, Keishi-bukuryo-gan, Byakko-ka-ninjin-to, Shakuyaku-kanzo-to and Sairei-to.

IPC 1-7

A61K 35/78; A61K 9/48

IPC 8 full level

A61K 9/16 (2006.01); A61K 9/48 (2006.01); A61K 36/00 (2006.01); A61K 36/23 (2006.01); A61K 36/258 (2006.01); A61K 36/28 (2006.01); A61K 36/539 (2006.01); A61K 36/718 (2006.01); A61K 36/725 (2006.01); A61K 36/744 (2006.01); A61K 36/756 (2006.01); A61K 36/9066 (2006.01)

CPC (source: EP US)

A61K 9/1611 (2013.01 - EP US); A61K 9/1652 (2013.01 - EP US); A61K 9/4858 (2013.01 - EP US); A61K 36/00 (2013.01 - EP US); A61K 36/23 (2013.01 - EP US); A61K 36/258 (2013.01 - EP US); A61K 36/28 (2013.01 - EP US); A61K 36/539 (2013.01 - EP US); A61K 36/718 (2013.01 - EP US); A61K 36/725 (2013.01 - EP US); A61K 36/744 (2013.01 - EP US); A61K 36/756 (2013.01 - EP US); A61K 36/9066 (2013.01 - EP US)

C-Set (source: EP US)

  1. A61K 36/00 + A61K 2300/00
  2. A61K 36/9066 + A61K 2300/00
  3. A61K 36/23 + A61K 2300/00
  4. A61K 36/258 + A61K 2300/00
  5. A61K 36/28 + A61K 2300/00
  6. A61K 36/539 + A61K 2300/00
  7. A61K 36/718 + A61K 2300/00
  8. A61K 36/725 + A61K 2300/00
  9. A61K 36/744 + A61K 2300/00
  10. A61K 36/756 + A61K 2300/00

Designated contracting state (EPC)

AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

EP 0530833 A1 19930310; EP 0530833 B1 19960417; AT E136785 T1 19960515; DE 69209942 D1 19960523; DE 69209942 T2 19960905; ES 2088523 T3 19960816; US 5318798 A 19940607

DOCDB simple family (application)

EP 92115192 A 19920904; AT 92115192 T 19920904; DE 69209942 T 19920904; ES 92115192 T 19920904; US 94180092 A 19920908