EP 0531452 A1 19930317 - SYNTHESIS OF GLYCEROL DI- AND TRIPHOSPHATE DERIVATIVES.
Title (en)
SYNTHESIS OF GLYCEROL DI- AND TRIPHOSPHATE DERIVATIVES.
Title (de)
SYNTHESE VON GLYCEROL, DI- UND TRIPHOSPHATDERIVATEN.
Title (fr)
SYNTHESE DE DERIVES DE DIPHOSPHATE ET DE TRIPHOSPHATE DE GLYCERINE.
Publication
Application
Priority
US 53055690 A 19900529
Abstract (en)
[origin: WO9118914A1] A process for the preparation of glycerophospholipid derivatives comprising coupling the phosphate group of a glycerol monophosphate derivative in which one of the phosphate hydroxyls is replaced by a leaving group, with the terminal phosphate group of a mono- or diphosphate compound or a salt thereof, in the presence of a basic catalyst, under anhydrous conditions.
Abstract (fr)
Procédé servant à la préparation de dérivés de glycérophospholipides comprenant le couplage du groupe phosphate d'un dérivé de monophosphate de glycérine dans lequel un des hydroxyles de phosphate est remplacé par un groupe partant, avec le groupe phosphate de terminaison d'un composé de mono- ou de diphospate ou un de ses sels, en présence d'un catalyseur basique, dans des conditions anhydres.
IPC 1-7
IPC 8 full level
A61K 31/715 (2006.01); A61P 31/12 (2006.01); C07F 9/10 (2006.01); C07F 9/40 (2006.01); C07F 9/6533 (2006.01); C07H 19/10 (2006.01); C07H 19/207 (2006.01)
CPC (source: EP)
A61P 31/12 (2017.12); C07F 9/10 (2013.01); C07F 9/409 (2013.01); C07F 9/6533 (2013.01); C07H 19/10 (2013.01); C07H 19/207 (2013.01)
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IT LI LU NL SE
DOCDB simple family (publication)
WO 9118914 A1 19911212; EP 0531452 A1 19930317; EP 0531452 A4 19930609; JP H05507279 A 19931021
DOCDB simple family (application)
US 9103736 W 19910529; EP 91912531 A 19910529; JP 51173091 A 19910529