Global Patent Index - EP 0535144 A4

EP 0535144 A4 19930811 - METHOD FOR HOMOLOGOUS RECOMBINATION IN ANIMAL AND PLANT CELLS

Title (en)

METHOD FOR HOMOLOGOUS RECOMBINATION IN ANIMAL AND PLANT CELLS

Publication

EP 0535144 A4 19930811 (EN)

Application

EP 91912599 A 19910607

Priority

  • US 53639790 A 19900612
  • US 53745890 A 19900614
  • US 59769490 A 19901017

Abstract (en)

[origin: WO9119796A1] A method for producing animal cells which contain a desired gene sequence which has been inserted into a predetermined gene sequence by homologous recombination. The method permits the production of animal cells which have subtle and precise modifications of gene sequence and expression.

IPC 1-7

C12N 15/00; C12N 5/00

IPC 8 full level

A01H 1/00 (2006.01); A01K 67/027 (2006.01); C12N 5/10 (2006.01); C12N 15/09 (2006.01); C12N 15/82 (2006.01); C12N 15/90 (2006.01)

CPC (source: EP)

A01K 67/0275 (2013.01); C12N 15/8213 (2013.01); C12N 15/902 (2013.01); A01K 2217/05 (2013.01)

Citation (search report)

  • [XP] WO 9014092 A1 19901129 - CELL GENESYS INC [US]
  • [X] MOLECULAR AND CELLULAR BIOLOGY vol. 9, no. 12, December 1989, WASHINGTON US pages 5500 - 5507 BAKER, M.D. 'High-frequency homologous recombination between duplicate chromosomal immunoglobulin mu heavy-chain constant regions'
  • NATURE, vol. 338, 09 March 1989, London (GB); A. ZIMMER et al., pp. 150-153
  • [X] NATURE vol. 338, 9 March 1989, LONDON GB pages 150 - 153 ZIMMER, A., ET AL. 'Production of chimaeric mice containing embryonic stem (ES) cells carrying a homoeobox Hox1.1 allele mutated by homologous recombination'
  • NATURE, vol. 350, 21 March 1991, London (GB); P. HASTY et al., pp. 243-246
  • [XP] NATURE vol. 350, 21 March 1991, LONDON GB pages 243 - 246 HASTY, P., ET AL. 'Introduction of a subtle mutation into the Hox-2.6 locus in embryonic stem cells'
  • [XP] MOLECULAR AND CELLULAR BIOLOGY vol. 10, no. 9, September 1990, WASHINGTON US pages 4466 - 4472 SHULMAN, M.J., ET AL. 'Homologous recombination in hybridoma cells: Dependence on time and fragment length'
  • [A] PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA vol. 76, no. 10, October 1979, WASHINGTON US pages 4951 - 4955 SCHERER, S., ET AL. 'Replacement of chromosome segments with altered DNA sequences constructed in vitro'
  • [A] GENE vol. 36, no. 1/2, 1985, AMSTERDAM NL pages 87 - 95 RUDOLPH, H., ET AL. 'One-step gene replacment in yeast by cotransformation'
  • PROCEEDINGS OF THE NATL. ACADEMY OF SCIENCES USA, vol. 85, November 1988, Washington, DC (US); DOETSCHMAN et al., pp. 8583-8587
  • MOLECULAR & CELLULAR BIOLOGY, vol. 10, February 1990; BAUR et al., pp. 492-500
  • NATURE, vol. 338, 09 March 1989; JOYNER et al., pp. 153-156
  • See references of WO 9119796A1

Designated contracting state (EPC)

AT BE CH DE DK ES FR GB GR IT LI LU NL SE

DOCDB simple family (publication)

WO 9119796 A1 19911226; AU 654284 B2 19941103; AU 8182391 A 19920107; CA 2084774 A1 19911213; EP 0535144 A1 19930407; EP 0535144 A4 19930811; JP H05507853 A 19931111

DOCDB simple family (application)

US 9104006 W 19910607; AU 8182391 A 19910607; CA 2084774 A 19910607; EP 91912599 A 19910607; JP 51176091 A 19910607