EP 0537222 A1 19930421 - IMMUNOREACTIVE COMPOUND.
Title (en)
IMMUNOREACTIVE COMPOUND.
Title (de)
IMMUNOREAKTIVE VERBINDUNG.
Title (fr)
COMPOSE IMMUNOREACTIF.
Publication
Application
Priority
EP 90201781 A 19900703
Abstract (en)
[origin: WO9200763A1] Novel immunoreactive compounds are provided which comprise one or more antigen-binding fragments of IgM or IgA coupled to a carrier molecule, such as HSA, an enzyme or a synthetic polypeptide of low immunogenicity. By coupling these fragments to the carrier their relatively low antigen affinity is restored to a level comparable with the affinity level of native IgM or IgA.
Abstract (fr)
On décrit des nouveaux composés immunoréactifs comprenant un ou plusieurs fragments de fixation de l'antigène de l'IgM ou l'IgA couplés à une molécule vectrice, telle que la sérumalbumine humaine (SAH), une enzyme ou un polypeptide synthétique de faible immunogénicité. Le couplage de ces fragments au vecteur permet de ramener leur relativement faible affinité aux antigènes à un niveau comparable au niveau d'affinité de l'IgM ou de l'IgA natif.
IPC 1-7
IPC 8 full level
A61K 39/395 (2006.01); A61K 47/48 (2006.01); C07K 16/06 (2006.01); G01N 33/532 (2006.01); G01N 33/574 (2006.01)
CPC (source: EP KR)
A61K 47/42 (2013.01 - KR); A61K 47/6889 (2017.07 - EP); C07K 16/065 (2013.01 - EP); G01N 33/532 (2013.01 - EP); G01N 33/57484 (2013.01 - EP)
Citation (search report)
See references of WO 9200763A1
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IT LI LU NL SE
DOCDB simple family (publication)
WO 9200763 A1 19920123; CA 2086531 A1 19920104; EP 0537222 A1 19930421; FI 925804 A0 19921221; FI 925804 A 19921221; HU 9204170 D0 19930428; HU T63343 A 19930830; JP H05507924 A 19931111; KR 930701201 A 19930611
DOCDB simple family (application)
EP 9101223 W 19910628; CA 2086531 A 19910628; EP 91911923 A 19910628; FI 925804 A 19921221; HU 417091 A 19910628; JP 51109391 A 19910628; KR 920703408 A 19921230