Global Patent Index - EP 0538267 A4

EP 0538267 A4 19940601 - MONOCLONAL ANTI-IGM ANTIBODIES, THEIR PRODUCTION AND USE, AND HYBRIDOMAS FOR PRODUCING THE SAME

Title (en)

MONOCLONAL ANTI-IGM ANTIBODIES, THEIR PRODUCTION AND USE, AND HYBRIDOMAS FOR PRODUCING THE SAME

Publication

EP 0538267 A4 19940601 (EN)

Application

EP 91909436 A 19910424

Priority

US 51597490 A 19900427

Abstract (en)

[origin: WO9117257A1] A principal aspect of the invention concerns rat monoclonal antibodies that: (a) bind selectively to IgM sub-type antibodies; (b) are IgGs; (c) do not bind to IgG1 or IgG2 sub-type. The preferred embodiment of these antibodies is one designated 2G10, and functional equivalents thereof.

IPC 1-7

C12P 21/08

IPC 8 full level

A61K 39/395 (2006.01); A61K 47/48 (2006.01); C07K 16/00 (2006.01); C07K 16/42 (2006.01); C12N 5/16 (2006.01); C12N 15/02 (2006.01); C12P 21/08 (2006.01); A61K 38/00 (2006.01)

CPC (source: EP)

A61K 47/6873 (2017.07); C07K 16/4283 (2013.01); A61K 38/00 (2013.01)

Citation (search report)

  • [X] US 4792447 A 19881220 - UHR JONATHAN W [US], et al
  • [E] WO 9207574 A1 19920514 - TANOX BIOSYSTEMS INC [US]
  • [XY] CHEMICAL ABSTRACTS, vol. 103, no. 17, 28 October 1985, Columbus, Ohio, US; abstract no. 134580t & UMEMOTO NAOJI ET AL.: "CONJUGATES OF MITOMYCIN C WITH TH IMMUNOGLOBULIN M MONOMER FRAGMENT OF A MONOCLONAL ANTI-mm46 IMMUNOGLOBULIN M ANTIBODY WITH OR WITHOUT SERUM ALBUMIN AS INTERMEDIARY.", J. APPL. BIOCHEM., vol. 6, no. 5, 1984, pages 297 - 307, XP008123489
  • [Y] TIMOTHY A. SPRINGER ET AL.: "MOAB'S SPECIFIC FOR RAT IGG1, IGG2, AND IGG2B SUBCLASSES, AND KAPPA CHAIN MONOTYPIC AND ALLOTYPIC DETERMINANTS: REAGENTS FOR USE WITH RAT MOAB'S.", HYBRIDOMA, vol. 1, no. 3, 1982, pages 257 - 273
  • [Y] DATABASE MEDLINE US NATIONAL LIBRARY OF MEDICINE (NLM), BETHESDA, MD, US; & ARMTIAGE RJ. ET AL.: "FUNCTIONAL INTERACTION BETWEEN B CELL SUBPOPULATIONS DEFINED BY CD23 EXPRESSION", EUR. J. IMMUNOL., vol. 18, no. 11, November 1988 (1988-11-01), pages 1753 - 1760
  • [Y] CHARLES L. SIDMAN ET AL.: "PROLIFERATIVE RESPONSE TO ANTI-IGM AN", JOURNAL OF IMMUNOLOGY, vol. 121, no. 6, December 1978 (1978-12-01), BALTIMORE US, pages 2129 - 2136
  • See references of WO 9117257A1

Designated contracting state (EPC)

AT BE CH DE DK ES FR GB GR IT LI LU NL SE

DOCDB simple family (publication)

WO 9117257 A1 19911114; AU 650659 B2 19940630; AU 7866491 A 19911127; CA 2079901 A1 19911028; CN 1057072 A 19911218; EP 0538267 A1 19930428; EP 0538267 A4 19940601; IE 911172 A1 19911106; IL 97827 A0 19920621; JP H06504424 A 19940526; NZ 237784 A 19920925; PT 97482 A 19920131; PT 97482 B 19980831; RU 2105062 C1 19980220; TW 349995 B 19990111; ZA 912695 B 19930224

DOCDB simple family (application)

US 9102822 W 19910424; AU 7866491 A 19910424; CA 2079901 A 19910424; CN 91102913 A 19910427; EP 91909436 A 19910424; IE 117291 A 19910408; IL 9782791 A 19910411; JP 50914491 A 19910424; NZ 23778491 A 19910410; PT 9748291 A 19910426; RU 92016351 A 19910424; TW 80103007 A 19910417; ZA 912695 A 19910411