EP 0538459 A1 19930428 - PHOSPHOLIPID-TARGETED THROMBOLYTIC AGENTS.
Title (en)
PHOSPHOLIPID-TARGETED THROMBOLYTIC AGENTS.
Title (de)
AUF PHOSPHOLIPIDE GERICHTETE THROMBOLYTISCHE SUBSTANZEN.
Title (fr)
AGENTS THROMBOLYTIQUES CIBLES SUR DES PHOSPHOLIPIDES.
Publication
Application
Priority
US 69736491 A 19910509
Abstract (en)
[origin: WO9219279A1] Conjugates with an affinity for phospholipids are disclosed. The conjugates comprise a first compound having affinity for phospholipids, with a binding constant that is not greater than about 10-7 M and a second compound that lyses thrombi or is a precursor of a compound that lyses thrombi.
Abstract (fr)
Conjugués présentant une affinité pour des phospholipides. Les conjugués comprenent un premier composé présentant une affinité pour des phospholipides, avec une constante de liaison non supérieure à environ 10-7 M, ainsi qu'un second composé lysant des thrombi ou constituant un précurseur d'un composé lysant des thrombi.
IPC 1-7
A61K 37/02; A61K 37/54; A61K 37/62; C07H 15/12; C07H 17/00; C07K 3/06; C07K 3/08; C07K 13/00; C12N 5/00; C12N 9/70; C12N 9/72
IPC 8 full level
A61K 38/00 (2006.01); A61K 38/43 (2006.01); A61K 38/46 (2006.01); A61P 7/02 (2006.01); C07K 14/315 (2006.01); C07K 14/47 (2006.01); C12N 9/70 (2006.01); C12N 9/72 (2006.01)
CPC (source: EP)
A61P 7/02 (2017.12); C07K 14/3153 (2013.01); C07K 14/4721 (2013.01); C12N 9/6456 (2013.01); A61K 38/00 (2013.01); C07K 2319/00 (2013.01); C07K 2319/33 (2013.01)
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IT LI LU MC NL SE
DOCDB simple family (publication)
WO 9219279 A1 19921112; CA 2086437 A1 19921110; EP 0538459 A1 19930428; EP 0538459 A4 19930616; JP H05508664 A 19931202; TW 239869 B 19950201
DOCDB simple family (application)
US 9203960 W 19920511; CA 2086437 A 19920511; EP 92913004 A 19920511; JP 51204692 A 19920511; TW 81105670 A 19920717