EP 0538459 A4 19930616 - PHOSPHOLIPID-TARGETED THROMBOLYTIC AGENTS
Title (en)
PHOSPHOLIPID-TARGETED THROMBOLYTIC AGENTS
Publication
Application
Priority
US 69736491 A 19910509
Abstract (en)
[origin: WO9219279A1] Conjugates with an affinity for phospholipids are disclosed. The conjugates comprise a first compound having affinity for phospholipids, with a binding constant that is not greater than about 10-7 M and a second compound that lyses thrombi or is a precursor of a compound that lyses thrombi.
IPC 1-7
A61K 37/02; A61K 37/54; A61K 37/62; C07H 15/12; C07H 17/00; C07K 3/06; C07K 3/08; C07K 13/00; C12N 5/00; C12N 9/70; C12N 9/72
IPC 8 full level
A61K 38/00 (2006.01); A61K 38/43 (2006.01); A61K 38/46 (2006.01); A61P 7/02 (2006.01); C07K 14/315 (2006.01); C07K 14/47 (2006.01); C12N 9/70 (2006.01); C12N 9/72 (2006.01)
CPC (source: EP)
A61P 7/02 (2017.12); C07K 14/3153 (2013.01); C07K 14/4721 (2013.01); C12N 9/6456 (2013.01); A61K 38/00 (2013.01); C07K 2319/00 (2013.01); C07K 2319/33 (2013.01)
Citation (search report)
- [Y] EP 0293567 A1 19881207 - BOEHRINGER SOHN INGELHEIM [DE]
- [XP] WO 9109953 A1 19910711 - ZYMOGENETICS INC [US]
- [XP] WO 9205749 A1 19920416 - NEW ENGLAND DEACONESS HOSPITAL [US]
- BIOLOGICAL CHEMISTRY HOPPE-SEYLER vol. 371, May 1990, BERLIN-NEW YORK pages 383 - 388 R\MISCH J. ET AL. 'Purification and characterization of six annexins from human placenta.'
- See references of WO 9219279A1
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IT LI LU MC NL SE
DOCDB simple family (publication)
WO 9219279 A1 19921112; CA 2086437 A1 19921110; EP 0538459 A1 19930428; EP 0538459 A4 19930616; JP H05508664 A 19931202; TW 239869 B 19950201
DOCDB simple family (application)
US 9203960 W 19920511; CA 2086437 A 19920511; EP 92913004 A 19920511; JP 51204692 A 19920511; TW 81105670 A 19920717