EP 0539573 A4 19931229 - GENOMIC MODIFICATIONS WITH HOMOLOGOUS DNA TARGETING
Title (en)
GENOMIC MODIFICATIONS WITH HOMOLOGOUS DNA TARGETING
Publication
Application
Priority
US 70050191 A 19910515
Abstract (en)
[origin: WO9220808A1] Methods are provided for modification of genomic target sites, where desired changes which can be small or subtle may be introduced into the target site to provide for modification of target genes or regulatory sequences. It is found that one may retain a marker without interference with the functioning of a target gene or select for excision of exogenous DNA to leave a single copy of the target gene with the modification.
IPC 1-7
IPC 8 full level
A61K 48/00 (2006.01); C07K 14/805 (2006.01); C12N 15/10 (2006.01); C12N 15/85 (2006.01); C12N 15/90 (2006.01); A61K 38/00 (2006.01)
CPC (source: EP)
A61K 48/00 (2013.01); C07K 14/805 (2013.01); C12N 15/102 (2013.01); C12N 15/85 (2013.01); C12N 15/907 (2013.01); A61K 38/00 (2013.01); C12N 2830/00 (2013.01); C12N 2830/15 (2013.01); C12N 2830/60 (2013.01); C12N 2830/85 (2013.01)
Citation (search report)
- [XP] WO9 119 796 (BAYLOR COLLEGE OF MEDICINE) 26 December 1991
- See references of WO 9220808A1
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IT LI LU MC NL SE
DOCDB simple family (publication)
WO 9220808 A1 19921126; AU 2140292 A 19921230; AU 664847 B2 19951207; CA 2092695 A1 19921116; EP 0539573 A1 19930505; EP 0539573 A4 19931229
DOCDB simple family (application)
US 9204054 W 19920513; AU 2140292 A 19920513; CA 2092695 A 19920513; EP 92913238 A 19920513