EP 0540650 A1 19930512 - GAMMA-CARBOXYLASE AND METHODS OF USE.
Title (en)
GAMMA-CARBOXYLASE AND METHODS OF USE.
Title (de)
GAMMA-CARBOXYLASE UND METHODEN DER ANWENDUNG.
Title (fr)
GAMMA-CARBOXYLASE ET PROCEDES D'UTILISATION.
Publication
Application
Priority
- US 55722090 A 19900723
- US 66973591 A 19910314
Abstract (en)
[origin: WO9201795A1] Protein compositions having gamma-carboxylase activity enriched at least 20,000-fold as compared to liver microsomes are provided. Also provided are DNA molecules encoding gamma-carboxylase. The protein compositions and DNA molecules are useful within methods of producing gamma-carboxylated vitamin K-dependent proteins.
Abstract (fr)
L'invention se rapporte à des compositions protéiques déployant une activité de gamma-carboxylase enrichie au moins 20.000 fois lorsqu'on la compare à celle de microsomes du foie. L'invention décrit également des molécules d'ADN codant pour la gamma-carboxylase. Ces compositions protéiques et ces molécules d'ADN sont utiles dans des procédés de production de protéines dépendant de la vitamine K gamma-carboxylée
IPC 1-7
C12N 5/10; C12N 9/88; C12N 15/10; C12N 15/12; C12N 15/57; C12N 15/60
IPC 8 full level
C12N 5/10 (2006.01); C12N 9/00 (2006.01); C12N 9/64 (2006.01); C12N 9/74 (2006.01); C12N 9/88 (2006.01); C12N 15/09 (2006.01); C12N 15/60 (2006.01); C12P 21/00 (2006.01); F02B 75/02 (2006.01)
CPC (source: EP)
C12N 9/647 (2013.01); C12N 9/88 (2013.01); F02B 2075/027 (2013.01)
Citation (search report)
See references of WO 9201795A1
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IT LI LU NL SE
DOCDB simple family (publication)
WO 9201795 A1 19920206; AU 8427091 A 19920218; CA 2087970 A1 19920124; EP 0540650 A1 19930512; IE 912600 A1 19920129; JP H05508551 A 19931202
DOCDB simple family (application)
US 9105177 W 19910722; AU 8427091 A 19910722; CA 2087970 A 19910722; EP 91914387 A 19910722; IE 260091 A 19910723; JP 51374091 A 19910722